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1. (WO2007087985) METHODS FOR INTERFERING WITH GLUCOCORTICOID INDUCED GASTRIC ACID SECRETION
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2007/087985    International Application No.:    PCT/EP2007/000350
Publication Date: 09.08.2007 International Filing Date: 17.01.2007
IPC:
G01N 33/68 (2006.01)
Applicants: MERCK PATENT GMBH [DE/DE]; Frankfurter Strasse 250, 64293 Darmstadt (DE) (For All Designated States Except US).
LANG, Florian [DE/DE]; (DE) (For US Only)
Inventors: LANG, Florian; (DE)
Common
Representative:
MERCK PATENT GMBH; Frankfurter Strasse 250, 64293 Darmstadt (DE)
Priority Data:
06001934.6 31.01.2006 EP
Title (EN) METHODS FOR INTERFERING WITH GLUCOCORTICOID INDUCED GASTRIC ACID SECRETION
(FR) PROCÉDÉ PERMETTANT D'INTERFÉRER AVEC LA SÉCRÉTION D'ACIDE GASTRIQUE INDUITE PAR GLUCOCORTICOÏDE
Abstract: front page image
(EN)A method for altering glucocorticoid induced gastric acid secretion comprising, contacting cells expressing serum and glucocorticoid inducible kinase (SGK) with a substance that modulates said glucocorticoid inducible kinase. Furthermore the invention relates to the diagnosis and to the identification of compounds that may be agonists, antagonists that are potentially useful in therapy of pathological gastric acid secretion.
(FR)La présente invention concerne un procédé permettant de modifier la sécrétion d'acide gastrique induite par un glucocorticoïde qui consiste à mettre en contact des cellules exprimant une kinase inductible par sérum et glucocorticoïde (SGK) avec une substance qui module cette kinase inductible par glucocorticoïde. Cette invention concerne aussi le diagnostic et l'identification de composés qui peuvent être des agonistes, des antagonistes potentiellement utiles dans une thérapie de sécrétion acide gastrique pathologique.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)