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Machine translation
1. (WO2007085957) PREPARATION OF PLATINUM (LL) COMPLEXES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2007/085957    International Application No.:    PCT/IB2007/000213
Publication Date: 02.08.2007 International Filing Date: 30.01.2007
IPC:
C07F 15/00 (2006.01)
Applicants: PLATCO TECHNOLOGIES (PROPRIETARY) LIMITED [ZA/ZA]; 152 Cape Road, Mill Park, 6001 Port Elizabeth (ZA) (For All Designated States Except US).
DU PREEZ, Jan, Gysbert, Hermanus [ZA/ZA]; (ZA) (For US Only)
Inventors: DU PREEZ, Jan, Gysbert, Hermanus; (ZA)
Agent: SPOOR & FISHER; P O BOX 454, 0001 Pretoria (ZA)
Priority Data:
60/762,871 30.01.2006 US
Title (EN) PREPARATION OF PLATINUM (LL) COMPLEXES
(FR) PREPARATION DE COMPLEXES DE PLATINE (II)
Abstract: front page image
(EN)This invention relates a method for the preparation of platinum(II) oxalato complexes from their dihalogenoplatinum(II) precursors having either neutral monodentate or bidentate non-leaving co-ligands. Of particular interest is oxaliplatin. The method includes the step of reacting a halogenoplatinum(II) complex containing a neutral monodentate or bidentate ligand with an oxalate in a non-aqueous solvent or a mixed solvent system. The mixed solvent system is solvent mixture containing a non-aqueous solvent and water. According to the present invention, the non-aqueous solvent is an alcohol.
(FR)La présente invention concerne un procédé de préparation de complexes oxalato-platine (II) à partir de leurs précurseurs dihalogénoplatine (II) possédant des co-ligands non partants monodentates ou bidentates neutres. L’oxaliplatine est d’un intérêt particulier. Le procédé comprend l'étape consistant à faire réagir un complexe halogénoplatine (II) contenant un ligand monodentate ou bidentate neutre avec un oxalate dans un solvant non aqueux ou un système de solvants mélangés. Le système de solvants mélangés est un mélange de solvants contenant un solvant non aqueux et de l'eau. Selon la présente invention, le solvant non aqueux est un alcool.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)