WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2007085205) PYRROLE SUBSTITUTED 2-INDOLINONE DERIVATIVES, THE PREPARATION METHODS AND MEDICAL USES THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2007/085205    International Application No.:    PCT/CN2007/000323
Publication Date: 02.08.2007 International Filing Date: 29.01.2007
IPC:
C07D 403/06 (2006.01), C07D 403/14 (2006.01), C07D 401/14 (2006.01), A61K 31/404 (2006.01), A61P 19/02 (2006.01), A61P 35/00 (2006.01)
Applicants: SHANGHAI HENGRUI PHARMACEUTICAL CO., LTD. [CN/CN]; No.279 Wenjing Road, Minhang District Shanghai 200245 (CN) (For All Designated States Except US).
TANG, Peng Cho [CN/CN]; (CN) (For US Only).
BIE, Pingyan [CN/CN]; (CN) (For US Only).
LIU, Weili [CN/CN]; (CN) (For US Only).
YANG, Shibo [CN/CN]; (CN) (For US Only).
ZHANG, Lei [CN/CN]; (CN) (For US Only)
Inventors: TANG, Peng Cho; (CN).
BIE, Pingyan; (CN).
LIU, Weili; (CN).
YANG, Shibo; (CN).
ZHANG, Lei; (CN)
Agent: JEEKAI & PARTNERS; Suite 602, Jinyu Tower A129 West Xuan Wu Men Street, Xicheng District Beijing 100031 (CN)
Priority Data:
200610003228.1 27.01.2006 CN
200610065002.4 15.03.2006 CN
Title (EN) PYRROLE SUBSTITUTED 2-INDOLINONE DERIVATIVES, THE PREPARATION METHODS AND MEDICAL USES THEREOF
(FR) DÉRIVÉS DE 2-INDOLINONE À SUBSTITUTION PYROLLE, LEURS PROCÉDÉS DE PRÉPARATION ET LEURS UTILISATIONS MÉDICALES
(ZH) 吡咯取代的2-二氢吲哚酮衍生物、其制法与医药上的用途
Abstract: front page image
(EN)The present application discloses the pyrrole substituted 2-indolinone derivatives of general formula (I), in which the substituents defined as the description, their pharmaceutically acceptable salts and the compositions thereof. The present application also discloses the preparation methods of the general formula(I), their uses for preventing and treating the protein kinase related cellular disorders, and their uses for preparing the protein kinase inhibitors.
(FR)L'invention concerne des dérivés de 2-indolinone à substitution pyrolle de formule générale (I), dans laquelle les substituants sont tels que définis dans la description, leurs sels de qualité pharmaceutique et leurs compositions. L'invention concerne également des procédés de préparation de la formule générale (I), leurs utilisations dans la prévention et le traitement de troubles cellulaires relatifs aux protéines kinases et leurs utilisations dans la préparation des inhibiteurs des protéines kinases.
(ZH)本发明涉及通式(I)所示的吡咯取代的2-二氢吲哚酮衍生物或其药学上可接受的盐,其中通式中的取代基如说明书所示,以及含有该衍生物的组合物。本发明还涉及通式(I)化合物的制备方法和其用于蛋白激酶相关性细胞功能障碍的预防和治疗用途,以及该化合物在制备蛋白激酶抑制剂中的用途。
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)