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1. (WO2007083182) NOVEL HETEROCYCLES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2007/083182    International Application No.:    PCT/IB2006/003468
Publication Date: 26.07.2007 International Filing Date: 01.12.2006
Chapter 2 Demand Filed:    23.10.2007    
IPC:
C07D 233/96 (2006.01), A61K 31/505 (2006.01)
Applicants: ORCHID RESEARCH LABORATORIES LIMITED [IN/IN]; Orchid Towers 313, Valluvar Kottam High Road Nungambakkam Chennai Tamil Nadu 600 034 (IN) (For All Designated States Except US).
SRINIVAS, Visweswara, Akella, Staya, Surya [IN/IN]; (IN) (For US Only).
TADIPARTHI, Ravikumar [IN/IN]; (IN) (For US Only).
SHARMA, Ganapavarapu, Veera, Raghava [IN/IN]; (IN) (For US Only).
THIRUNAVUKKARASU, Sappanimuthu [IN/IN]; (IN) (For US Only).
BHAKIARAJ, Durairaj, Peter [IN/IN]; (IN) (For US Only).
KACHHADIA, Virendra [IN/IN]; (IN) (For US Only).
NARSIMHAN, Kilambi [IN/IN]; (IN) (For US Only).
THARA, Sathya, Narayana [IN/IN]; (IN) (For US Only).
RAJAGOPAL, Sriram [IN/IN]; (IN) (For US Only).
REEDY, Gaddam, Om [IN/IN]; (IN) (For US Only).
NARAYANAN, Sukunath [IN/IN]; (IN) (For US Only).
PARAMESWARAN, Venkatesan [IN/IN]; (IN) (For US Only).
JANARTHANAM, Venkatesan [IN/IN]; (IN) (For US Only)
Inventors: SRINIVAS, Visweswara, Akella, Staya, Surya; (IN).
TADIPARTHI, Ravikumar; (IN).
SHARMA, Ganapavarapu, Veera, Raghava; (IN).
THIRUNAVUKKARASU, Sappanimuthu; (IN).
BHAKIARAJ, Durairaj, Peter; (IN).
KACHHADIA, Virendra; (IN).
NARSIMHAN, Kilambi; (IN).
THARA, Sathya, Narayana; (IN).
RAJAGOPAL, Sriram; (IN).
REEDY, Gaddam, Om; (IN).
NARAYANAN, Sukunath; (IN).
PARAMESWARAN, Venkatesan; (IN).
JANARTHANAM, Venkatesan; (IN)
Agent: SHUKLA, Vibha; K & S Partners, 84-C, C-6 Lane, Off Central Avenue, Sainik Farms, New Delhi 110 062 (IN)
Priority Data:
0086/CHE/2006 19.01.2006 IN
Title (EN) NOVEL HETEROCYCLES
(FR) NOUVEAUX HÉTÉROCYCLES
Abstract: front page image
(EN)The present invention relates to novel heterocyclic compounds of the general formula (I), their derivatives, analogs, tautomeric forms, stereoisomers, polymorphs, hydrates, solvates, pharmaceutically acceptable salts and compositions, metabolites and prodrugs thereof. The present invention more particularly provides novel hetereocycles of the general formula (I). Also included is a method of treatment of immunological diseases, inflammation, pain disorder, rheumatoid arthritis; osteoporosis; multiple myeloma; uveititis; acute and chronic myelogenous leukemia; ischemic heart disease; atherosclerosis; cancer; ischemic-induced cell damage; pancreatic beta cell destruction; osteoarthritis; rheumatoid spondylitis; gouty arthritis; inflammatory bowel disease; adult respiratory distress syndrome (ARDS); psoriasis; Crohn's disease; allergic rhinitis; ulcerative colitis; anaphylaxis; contact dermatitis; muscle degeneration; cachexia; asthma; bone resorption diseases; ischemia reperfusion injury; brain trauma; multiple sclerosis; sepsis; septic shock; toxic shock syndrome; fever, and myalgias due to infection in a mammal comprising administering an effective amount of a compound of formula (I) as described above.
(FR)L'invention concerne de nouveaux composés hétérocycliques de formule générale (I), leurs dérivés, analogues, formes tautomères, stéréoisomères, polymorphes, hydrates, solvates, sels et compositions pharmaceutiquement acceptables, métabolites et promédicaments de ces composés. L'invention concerne plus particulièrement de nouveaux hétérocycles de formule générale (I). L'invention concerne en outre un procédé de traitement de maladies immunologiques, inflammation, troubles dus à la douleur, polyarthrite rhumatoïde; ostéoporose, myélome multiple; uvéite; leucémie myélogène aiguë ou chronique; maladies cardiaques ischémiques; athérosclérose; cancer; dégâts cellulaires ischémiques; destruction cellulaire; destruction cellules bêta pancréatiques; ostéoarthrite; spondylitis rhumatoïde; arthrite goutteuse; inflammation de l'intestin; syndrome de détresse respiratoire aigu (ARDS); psoriasis, maladie de Crohn; rhinite allergique; rectocolite hémorragique; anaphhylaxie; desmatite par contact; dégénérescence musculaire; cachéxie; asthme; maladies de résorption osseuse; lésion ischémique reperfusion; traumatisme cranien; sclérose en plaques; sepsie; choc septique; syndrome choc toxique; fièvre; myalgie due à une infection chez un mammifère, ledit procédé comprenant l'administration d'une quantité efficace d'un composé de formule (I) tel que précédemment décrit.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)