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1. (WO2007080270) NEW CHOLEST-4-EN-3-ONE OXIME DERIVATIVES, PHARMACEUTICAL COMPOSITIONS COMPRISING THEM, AND PREPARATION PROCESS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2007/080270    International Application No.:    PCT/FR2006/002740
Publication Date: 19.07.2007 International Filing Date: 15.12.2006
IPC:
C07J 41/00 (2006.01), A61K 31/575 (2006.01), A61P 25/28 (2006.01), A61P 25/00 (2006.01)
Applicants: TROPHOS [FR/FR]; Parc Scientifique de Luminy, Luminy Biotech Entreprises, Case 931, F-13288 Marseille Cedex 9 (FR) (For All Designated States Except US).
DROUOT, Cyrille [FR/FR]; (FR) (For US Only).
MAUX, Delphine [FR/FR]; (FR) (For US Only)
Inventors: DROUOT, Cyrille; (FR).
MAUX, Delphine; (FR)
Agent: SANTARELLI; Bureau de Marseille, 146, rue Paradis, F-13294 Marseille Cedex 6 (FR)
Priority Data:
0512947 20.12.2005 FR
Title (EN) NEW CHOLEST-4-EN-3-ONE OXIME DERIVATIVES, PHARMACEUTICAL COMPOSITIONS COMPRISING THEM, AND PREPARATION PROCESS
(FR) NOUVEAUX DERIVES DE L'OXIME DE CHOLEST-4-EN-3-ONE, COMPOSITIONS PHARMACEUTIQUES LES RENFERMANT, ET PROCEDE DE PREPARATION
Abstract: front page image
(EN)Compound of the formula (I) in which X represents an oxygen atom or an =N-OH group and R represents a group selected from (II) or one of its esters and/or its addition salts with pharmaceutically acceptable acids, particularly as a cytoprotective, preferably cardioprotective and/or neuroprotective, medicament; the compounds of formula I in which R is R2, R3, R4, R5 or R6, as new compounds; and also their preparation process, and the use.
(FR)L'invention a pour objet I'utilisation à titre de médicament d'un composé répondant a Ia formule (I) ou de I'un de ses esters et/ou de ses sels d'addition avec les acides pharmaceutiquement acceptables, particulièrement comme médicament cytoprotecteur, préfèrentiellement cardioprotecteur et/ou neuroprotecteur.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: French (FR)
Filing Language: French (FR)