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1. (WO2007078895) MODIFIED RELEASE FORMULATIONS OF TRAMADOL AND USES THEREOF
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2007/078895 International Application No.: PCT/US2006/048100
Publication Date: 12.07.2007 International Filing Date: 18.12.2006
IPC:
A01N 33/02 (2006.01) ,A61K 31/135 (2006.01)
A HUMAN NECESSITIES
01
AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
N
PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
33
Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds
02
Amines; Quaternary ammonium compounds
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
13
Amines, e.g. amantadine
135
having aromatic rings, e.g. methadone
Applicants:
BIOVAIL LABORATORIES INTERNATIONAL S.R.L. [BB/BB]; Chelston Park, Building 2 Collymore Orck St. Michael, BB (AllExceptUS)
MAMAJIWALLA, Salim [MY/CA]; CA (UsOnly)
FRISBEE, Steve [US/US]; US (UsOnly)
Inventors:
MAMAJIWALLA, Salim; CA
FRISBEE, Steve; US
Agent:
TREANOR, Richard, L. ; Oblon, Spivak, McClelland, Maier & Neustadt, P.C. 1940 Duke Street Alexandria, VA 22314, US
Priority Data:
60/754,63130.12.2005US
60/754,63430.12.2005US
60/754,63730.12.2005US
Title (EN) MODIFIED RELEASE FORMULATIONS OF TRAMADOL AND USES THEREOF
(FR) FORMULATIONS DE TRAMADOL À LIBÉRATION MODIFIÉE ET LEURS UTILISATIONS
Abstract:
(EN) The present invention relates to specific types of controlled and modified release dosage forms containing tramadol or at least one pharmaceutically acceptable salt, enantiomer, or metabolite- thereof, that possess specific pharmacokinetic properties and which desirably are not subject to dose dumping, e.g., induced by food or alcohol. The invention also relate to methods of making and using these controlled and modified release dosage forms in therapeutic regimens wherein tramadol is therapeutically effective.
(FR) La présente invention concerne des types spécifiques de formes de dose à libération contrôlée et modifiée contenant du tramadol ou au moins un de ses sels, énantiomères ou métabolites pharmaceutiquement acceptables qui possèdent des propriétés pharmacocinétiques spécifiques et qui, de manière souhaitable, ne sont pas sujets à une chute de la dose induite par exemple par les aliments ou l'alcool. L'invention concerne également des procédés de préparation et d'utilisation de ces formes de dose à libération contrôlée et modifiée dans des schémas thérapeutiques dans lesquels le tramadol possède une efficacité thérapeutique.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)