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Machine translation
1. (WO2007076391) TGF-BETA BINDING COMPOSITIONS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2007/076391    International Application No.:    PCT/US2006/062397
Publication Date: 05.07.2007 International Filing Date: 20.12.2006
IPC:
C07K 16/22 (2006.01), A61K 39/395 (2006.01)
Applicants: ELI LILLY AND COMPANY [US/US]; Lilly Corporate Center, Indianapolis, Indiana 46285 (US) (For All Designated States Except US).
JONES, Bryan, Edward [US/US]; (US) (For US Only).
PANCOOK, James, D. [US/US]; (US) (For US Only).
ROWLINSON, Scott, William [AU/US]; (US) (For US Only)
Inventors: JONES, Bryan, Edward; (US).
PANCOOK, James, D.; (US).
ROWLINSON, Scott, William; (US)
Agent: XIE, Congping; Eli Lilly and Company, Patent Division, P. O. Box 6288, Indianapolis, Indiana 46206-6288 (US)
Priority Data:
60/753,956 23.12.2005 US
Title (EN) TGF-BETA BINDING COMPOSITIONS
(FR) COMPOSITIONS SE LIANT AUX TGF-BETA
Abstract: front page image
(EN)The present invention provides very high affinity antibodies, or antigen-binding fragments thereof, that neutralize mature human TGF-&bgr;l, TGF-&bgr;2, and TGF-&bgr;3. The antibodies of the invention are useful for treating cell proliferative disorders in a mammal.
(FR)La présente invention concerne des anticorps présentant une affinité très élevée, ou les fragments se liant aux antigènes de ces anticorps, neutralisant les TGF-&bgr;l, TGF-&bgr;2 et TGF-&bgr;3 matures de l’homme. Les anticorps selon l’invention sont utiles pour le traitement des troubles liés à la prolifération cellulaire chez les mammifères.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)