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1. (WO2007076117) LIPOSOMAL FORMULATIONS COMPRISING SECONDARY AND TERTIARY AMINES AND METHODS FOR PREPARING THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2007/076117    International Application No.:    PCT/US2006/049245
Publication Date: 05.07.2007 International Filing Date: 22.12.2006
IPC:
A61K 9/127 (2006.01)
Applicants: CELATOR PHARMACEUTICALS, INC. [US/US]; 303b College Road East, Princeton, NJ 08540 (US) (For All Designated States Except US).
DICKO, Awa [CA/CA]; (CA) (For US Only).
TARDI, Paul [CA/CA]; (CA) (For US Only).
MAYER, Lawrence [CA/CA]; (CA) (For US Only).
JOHNSTONE, Sharon [CA/CA]; (CA) (For US Only)
Inventors: DICKO, Awa; (CA).
TARDI, Paul; (CA).
MAYER, Lawrence; (CA).
JOHNSTONE, Sharon; (CA)
Agent: HILL, Laurie, L.; 12531 High Bluff Drive, Suite 100, San Diego, CA 92130-2040 (US)
Priority Data:
60/753,644 22.12.2005 US
Title (EN) LIPOSOMAL FORMULATIONS COMPRISING SECONDARY AND TERTIARY AMINES AND METHODS FOR PREPARING THEREOF
(FR) FORMULATIONS LIPOSOMALES COMPOSÉES D'AMINES SECONDAIRES ET TERTIAIRES ET PROCÉDÉS DE PRÉPARATION DESDITES FORMULATIONS
Abstract: front page image
(EN)Provided herein are liposomal compositions comprising a therapeutic agent having a protonatable amino group and a secondary or tertiary amine, and methods for encapsulating such therapeutic agents. In one aspect, the present invention relates to liposomal formulations comprising irinotecan in a triethanolamine solution, and optionally comprising copper gluconate, and methods for preparing the same.
(FR)L'invention concerne des compositions liposomales composées d'un agent thérapeutique, qui présente un groupe amino pouvant être protoné et une amine secondaire ou tertiaire, ainsi que des procédés d'encapsulation desdits agents thérapeutiques. Un aspect de la présente invention concerne des formulations liposomales, composées d'irinotécan dans une solution de triéthanolamine et éventuellement de gluconate de cuivre, ainsi que des procédés de préparation desdites formulations.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)