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1. (WO2007075595) BIOFILM ASSAY
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2007/075595    International Application No.:    PCT/US2006/048285
Publication Date: 05.07.2007 International Filing Date: 19.12.2006
IPC:
C12Q 1/22 (2006.01), G01N 33/569 (2006.01)
Applicants: VERTEX PHARMACUETICALS INCORPORATED [US/US]; 130 Waverly Street, Cambridge, MA 02139-4242 (US) (For All Designated States Except US).
BARTELS, Douglas, John [US/US]; (US) (For US Only)
Inventors: BARTELS, Douglas, John; (US)
Agent: O'BRIEN, Jonathan, P.; MILLER, CANFIELD, PADDOCK AND STONE, 444 West Michigan Avenue, Kalamazoo, MI 49007 (US)
Priority Data:
60/751,790 20.12.2005 US
Title (EN) BIOFILM ASSAY
(FR) ESSAI DE BIOFILM
Abstract: front page image
(EN)The invention describes methods for measuring biofilms or biofilm formation by microorganisms using compounds that fluoresce upon contacting certain biofilms, e.g. thioflavin, styrylbenzene, and naphthalene derivates. The methods can be used to detect biofilms in vitro and in vivo, and to screen for compounds that modulate biofilms.
(FR)L'invention concerne des procédés pour mesurer des biofilms ou la formation de biofilms par des micro-organismes à l'aide de composés qui sont fluorescents lors de la mise en contact avec certains biofilms. Les procédés peuvent être utilisés pour détecter des biofilms in vitro et in vivo, et filtrer des composés qui modulent des biofilms.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)