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1. (WO2007075335) MODULATION OF IN UTERO IMMUNE PROGRAMMING
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2007/075335    International Application No.:    PCT/US2006/047458
Publication Date: 05.07.2007 International Filing Date: 12.12.2006
IPC:
A61K 39/00 (2006.01)
Applicants: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA [US/US]; 1111 Franklin Street, 5th Floor, Oakland, CA 94607-5200 (US) (For All Designated States Except US).
PALINSKI, Wulf [US/US]; (US) (For US Only).
YAMASHITA, Tomoya [JP/JP]; (JP) (For US Only)
Inventors: PALINSKI, Wulf; (US).
YAMASHITA, Tomoya; (JP)
Agent: BAKER, Joseph, R.; Buchanan Ingersoll And Rooney LLP, 12230 El Camino Real, Suite 300, San Diego, CA 92130 (US)
Priority Data:
60/751,029 16.12.2005 US
Title (EN) MODULATION OF IN UTERO IMMUNE PROGRAMMING
(FR) MODULATION DE LA PROGRAMMATION IMMUNITAIRE IN UTERO
Abstract: front page image
(EN)Maternal adaptive immunity conveys temporary humoral immune protection to neonates. The disclosure demonstrates the influence of the in utero environment on adult atherosclerosis and provides evidence for persistent effects of maternal immunization on adult immune responses. The disclosure provides methods and compositions useful for immunization and more particularly for actively modulating the fetal programming of the immune system for the purpose preventing or treating immune -modulated diseases.
(FR)L'immunité adaptative maternelle confère une protection immunitaire humorale temporaire aux nouveau-nés. L'invention démontre l'influence de l'environnement in utero sur l'athérosclérose de l'adulte et prouve l'existence d'effets persistants de l'immunisation maternelle sur les réponses immunitaires de l'adulte. L'invention concerne des méthodes et des compositions utiles pour l'immunisation, et plus particulièrement pour moduler activement la programmation foetale du système immunitaire en vue de prévenir ou traiter des maladies modulées par le système immunitaire.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)