WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |

Search International and National Patent Collections
World Intellectual Property Organization
Machine translation
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2007/074904    International Application No.:    PCT/JP2006/326256
Publication Date: 05.07.2007 International Filing Date: 28.12.2006
A61K 9/08 (2006.01), A61K 31/7052 (2006.01), A61K 47/10 (2006.01), A61K 47/12 (2006.01), A61K 47/18 (2006.01)
Applicants: WAKAMOTO PHARMACEUTICAL CO., LTD. [JP/JP]; 5-3, Nihonbashimuromachi 1-chome Chuo-ku, Tokyo 1038330 (JP) (For All Designated States Except US).
YODA, Kouhei [JP/JP]; (JP) (For US Only).
KATO, Azusa [JP/JP]; (JP) (For US Only).
SUZUKI, Hidekazu [JP/JP]; (JP) (For US Only).
KOICHI, Kuniko [JP/JP]; (JP) (For US Only)
Inventors: YODA, Kouhei; (JP).
KATO, Azusa; (JP).
SUZUKI, Hidekazu; (JP).
KOICHI, Kuniko; (JP)
Agent: YASUTOMI, Yasuo; MT-2 BLDG. 5-36, Miyahara 3-chome Yodogawa-ku, Osaka-shi Osaka 5320003 (JP)
Priority Data:
2005-376739 28.12.2005 JP
(JA) 水性医薬組成物
Abstract: front page image
(EN)It is intended to provide an aqueous pharmaceutical composition with a sufficient preservative effect without adding a preservative. The invention relates to the aqueous pharmaceutical composition characterized by having a preservative effect by incorporating a medicinal substance and not incorporating sodium chloride and a preservative; and a method for obtaining a preservative effect by incorporating a medicinal substance in the composition without adding sodium chloride and a preservative thereto. As the medicinal substance incorporated in the composition of the invention, an antimicrobial agent is preferred and a macrolide antibiotic is particularly preferred. Further, one or more compounds selected from the group consisting of sugar alcohols and polyhydric alcohols may be added to the composition of the invention.
(FR)L’invention concerne une composition pharmaceutique aqueuse ayant un effet conservateur suffisant sans ajout d’agent de conservation. Ladite composition pharmaceutique aqueuse est caractérisée par un effet conservateur obtenu en incorporant une substance médicinale et sans incorporer de chlorure de sodium ni d’agent de conservation. L’invention concerne également une méthode pour obtenir un effet conservateur en incorporant une substance médicinale dans la composition sans ajouter de chlorure de sodium ni d’agent de conservation. Un agent antimicrobien est préféré et un antibiotique macrolide est particulièrement préféré comme substance médicinale incorporée à la composition de l'invention. De plus, un ou plusieurs composés sélectionnés parmi le groupe qui comprend des alcools de sucre et des alcools polyhydriques peuvent être ajoutés à la composition de l'invention.
(JA)本発明の目的は、保存剤を加えずに、十分な保存効力を有する水性医薬組成物を提供することである。 本発明は、薬物を含有し、塩化ナトリウム及び保存剤を含まないことにより保存効力を有することを特徴とする水性医薬組成物;及び、組成中に薬物を含有し、塩化ナトリウム及び保存剤を加えないことで保存効力を得る方法に関する。本発明の組成物に含有させる薬物としては、抗菌剤が好ましく、特にマクロライド系抗生物質が好ましい。本発明の組成物には、さらに糖アルコール類及び多価アルコール類からなる群から選ばれる少なくとも1種を添加することが出来る。
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)