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1. WO2007068354 - MEANS AND METHODS FOR THE TREATMENT OF TUMOROUS DISEASES

Publication Number WO/2007/068354
Publication Date 21.06.2007
International Application No. PCT/EP2006/011466
International Filing Date 29.11.2006
IPC
C07K 16/46 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
46Hybrid immunoglobulins
C07K 16/28 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18against material from animals or humans
28against receptors, cell surface antigens or cell surface determinants
A61K 39/395 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
A61P 35/02 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
02specific for leukemia
CPC
A61K 2039/505
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
505comprising antibodies
A61K 39/39558
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
395Antibodies
39533against materials from animals
39558against tumor tissues, cells, antigens
A61K 45/06
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
45Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
A61P 35/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
A61P 35/02
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
02specific for leukemia
C07K 16/2803
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
18against material from animals or humans
28against receptors, cell surface antigens or cell surface determinants
2803against the immunoglobulin superfamily
Applicants
  • MICROMET AG [DE]/[DE] (AllExceptUS)
  • BAEUERLE, Patrick [DE]/[DE] (UsOnly)
  • KUFER, Peter [DE]/[DE] (UsOnly)
  • KLINGER, Matthias [DE]/[DE] (UsOnly)
  • LEO, Eugen [DE]/[DE] (UsOnly)
Inventors
  • BAEUERLE, Patrick
  • KUFER, Peter
  • KLINGER, Matthias
  • LEO, Eugen
Agents
  • VOSSIUS & PARTNER
Priority Data
05027606.216.12.2005EP
06004144.901.03.2006EP
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) MEANS AND METHODS FOR THE TREATMENT OF TUMOROUS DISEASES
(FR) MOYENS ET PROCEDES POUR LE TRAITEMENT DE MALADIES TUMORALES
Abstract
(EN) Provided are pharmaceutical means and methods for the prevention, treatment or amelioration of indolent or aggressive B cell non-Hodgkin lymphoma (B NHL) and B cell leukemia comprising the administration of a bispecific single chain antibody construct to a subject in the need thereof and the use of said bispecific single chain antibody construct for the preparation of a pharmaceutical composition for the prevention, treatment or amelioration of indolent or aggressive B cell non-Hodgkin lymphoma (B NHL) and B cell leukemia, whereby said construct is to be administered for at least 1 week in specified daily doses. Moreover, the invention relates to kits comprising a bispecific single chain antibody construct to be used in accordance with this invention.
(FR) La présente invention concerne des moyens et des procédés pharmaceutiques destinés à la prévention, au traitement ou à l’atténuation de lymphomes B non hodgkiniens peu évolutifs ou agressifs (B NHL) et de leucémies B, comprenant l’administration d’une construction d’anticorps bispécifique à chaîne unique à un sujet en ayant besoin et l’utilisation de ladite construction pour la préparation d’une composition pharmaceutique destinée à la prévention, au traitement ou à l’atténuation de lymphomes B non hodgkiniens peu évolutifs ou agressifs (B NHL) et de leucémies B. Ladite construction d être administrée pendant au moins 1 semaine aux doses quotidiennes précisées. L’invention concerne en outre des kits comprenant une construction d’anticorps bispécifique à chaîne unique à utiliser selon cette invention.
Related patent documents
RU2008129080This application is not viewable in PATENTSCOPE because the national phase entry has not been published yet or the national entry is issued from a country that does not share data with WIPO or there is a formatting issue or an unavailability of the application.
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