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1. (WO2007064521) MORINDA CITRIFOLIA LEAF JUICE AND LEAF EXTRACT BASED FORMULATIONS

Pub. No.:    WO/2007/064521    International Application No.:    PCT/US2006/044949
Publication Date: Fri Jun 08 01:59:59 CEST 2007 International Filing Date: Wed Nov 22 00:59:59 CET 2006
IPC: A61K 36/746
A61K 36/00
Applicants: TAHITIAN NONI INTERNATIONAL, INC.
PALU, Afa, Kehaati
ZHOU, Bing-Nan
SU, Chen, Xing
JENSEN, Claude, Jarakae
WEST, Brett, Justin
STORY, Stephen, P.
Inventors: PALU, Afa, Kehaati
ZHOU, Bing-Nan
SU, Chen, Xing
JENSEN, Claude, Jarakae
WEST, Brett, Justin
STORY, Stephen, P.
Title: MORINDA CITRIFOLIA LEAF JUICE AND LEAF EXTRACT BASED FORMULATIONS
Abstract:
A method and composition for inhibiting certain enzymes, where such inhibition results in various health benefits is provided. More particularly, a method and composition using one or more of the following: Noni Leaf Extract; Noni Leaf Juice; and/or Roast Leaf to inhibit the following: HMG-CoA Reductase; Phosphodiesterases (3 and 4) PDE3 and PDE4; 5 -Lipoxygenase (LOX) and 15-LOX; Xanthine Oxidase (XO); Gamma Amino Butyric Acid (GABA) and the growth of the second most common human skin cancer cell line, is provided. Moreover, the foregoing enzymatic inhibitions result in: alleviating pain and inflammation; treating prostate cancers; lowering cholesterol levels; counteracting Diabetes Type II; maintaining the highest possible integrity of cellular interactions in the brain resulting in an undisturbed neural function, (i.e., neuroprotection); ameliorating the effects of asthma and allergies; improving energy; improving insulin secretion; decreasing kidney stone accumulation; alleviating the effects of gout; minimizing convulsions related to epilepsy and other seizure disorders; and providing palliative effects to those addicted to drugs.