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1. (WO2007054693) USE OF PYRROLOQUINOLINE COMPOUNDS TO KILL CLINICALLY LATENT MICROORGANISMS
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2007/054693 International Application No.: PCT/GB2006/004178
Publication Date: 18.05.2007 International Filing Date: 08.11.2006
IPC:
A61K 31/4439 (2006.01) ,C07D 471/04 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
435
having six-membered rings with one nitrogen as the only ring hetero atom
44
Non-condensed pyridines; Hydrogenated derivatives thereof
4427
containing further heterocyclic ring systems
4439
containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
471
Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/-C07D463/251
02
in which the condensed system contains two hetero rings
04
Ortho-condensed systems
Applicants:
BECK, Petra, Helga [DE/GB]; GB (UsOnly)
BROWN, Marc, Barry [GB/GB]; GB (UsOnly)
CLARK, David, Edward [GB/GB]; GB (UsOnly)
COATES, Anthony [GB/GB]; GB (UsOnly)
DYKE, Hazel, Joan [GB/GB]; GB (UsOnly)
HU, Yanmin [GB/GB]; GB (UsOnly)
LONDESBROUGH, Derek, John [GB/GB]; GB (UsOnly)
MILLS, Keith [GB/GB]; GB (UsOnly)
PALLIN, Thomas, David [GB/GB]; GB (UsOnly)
REID, Gary, Patrick [GB/GB]; GB (UsOnly)
STODDART, Gerlinda [GB/GB]; GB (UsOnly)
HELPERBY THERAPEUTICS LIMITED [GB/GB]; 20/24 Park Street Selby North Yorks YO8 4PW, GB (AllExceptUS)
Inventors:
BECK, Petra, Helga; GB
BROWN, Marc, Barry; GB
CLARK, David, Edward; GB
COATES, Anthony; GB
DYKE, Hazel, Joan; GB
HU, Yanmin; GB
LONDESBROUGH, Derek, John; GB
MILLS, Keith; GB
PALLIN, Thomas, David; GB
REID, Gary, Patrick; GB
STODDART, Gerlinda; GB
Agent:
SNODIN, Michael, D.; Potter Clarkson LLP Park View House 58 The Ropewalk Nottingham NG1 5DD, GB
Priority Data:
0522715.208.11.2005GB
Title (EN) USE OF PYRROLOQUINOLINE COMPOUNDS TO KILL CLINICALLY LATENT MICROORGANISMS
(FR) UTILISATION DE DÉRIVÉS DE PYRROLOQUINOLINE POUR L'ÉLIMINATION DE MICRO-ORGANISMES PERSISTANTS AU NIVEAU CLINIQUE
Abstract:
(EN) There is provided the use of compounds of formula (I), wherein R1 R2 R3 and X have meanings given in the description, for the preparation of a medicament for killing clinically latent microorganisms. There is also provided the use of compounds of formula (I) for treating microbial infections, as well as certain compounds of formula (I) per se.
(FR) La présente invention porte sur l'utilisation de composés de formule (I), où R1 R2 R3 et X ont les valeurs données dans la description, dans l'élaboration d'un médicament pour l'élimination de micro-organismes persistants au niveau clinique. La présente invention porte également sur l'utilisation des composés de formule (I) dans le traitement d'infections microbiennes, ainsi que sur certains composés de formule (I) en eux-mêmes.
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Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)