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1. WO2007045369 - DIFLUOROPHENOL DERIVATIVES AND THEIR USE

Publication Number WO/2007/045369
Publication Date 26.04.2007
International Application No. PCT/EP2006/009726
International Filing Date 09.10.2006
IPC
C07D 257/04 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
257Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
02not condensed with other rings
04Five-membered rings
C07C 229/14 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
229Compounds containing amino and carboxyl groups bound to the same carbon skeleton
02having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
04the carbon skeleton being acyclic and saturated
06having only one amino and one carboxyl group bound to the carbon skeleton
10the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings
14to carbon atoms of carbon skeletons containing rings
C07C 57/42 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
57Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
30containing six-membered aromatic rings
42having unsaturation outside the rings
A61K 31/41 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
41having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole
A61K 31/195 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
19Carboxylic acids, e.g. valproic acid
195having an amino group
A61P 9/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
9Drugs for disorders of the cardiovascular system
CPC
A61P 1/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1Drugs for disorders of the alimentary tract or the digestive system
A61P 11/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11Drugs for disorders of the respiratory system
A61P 11/06
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11Drugs for disorders of the respiratory system
06Antiasthmatics
A61P 13/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
13Drugs for disorders of the urinary system
A61P 13/08
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
13Drugs for disorders of the urinary system
08of the prostate
A61P 15/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
15Drugs for genital or sexual disorders
Applicants
  • BAYER HEALTHCARE AG [DE]/[DE] (AllExceptUS)
  • BARTEL, Stephan [DE]/[DE] (UsOnly)
  • HAHN, Michael [DE]/[DE] (UsOnly)
  • MORADI, Wahed, Ahmed [DE]/[DE] (UsOnly)
  • BECKER, Eva-Maria [DE]/[DE] (UsOnly)
  • RÖLLE, Thomas [DE]/[DE] (UsOnly)
  • STASCH, Johannes-Peter [DE]/[DE] (UsOnly)
  • SCHLEMMER, Karl-Heinz [DE]/[DE] (UsOnly)
  • WUNDER, Frank [DE]/[DE] (UsOnly)
  • KNORR, Andreas [DE]/[DE] (UsOnly)
Inventors
  • BARTEL, Stephan
  • HAHN, Michael
  • MORADI, Wahed, Ahmed
  • BECKER, Eva-Maria
  • RÖLLE, Thomas
  • STASCH, Johannes-Peter
  • SCHLEMMER, Karl-Heinz
  • WUNDER, Frank
  • KNORR, Andreas
Common Representative
  • BAYER HEALTHCARE AG
Priority Data
10 2005 050 497.321.10.2005DE
Publication Language German (DE)
Filing Language German (DE)
Designated States
Title
(DE) DIFLUORPHENOL-DERIVATE UND IHRE VERWENDUNG
(EN) DIFLUOROPHENOL DERIVATIVES AND THEIR USE
(FR) DERIVES DE DIFLUOROPHENOL ET LEUR UTILISATION
Abstract
(DE)
Die vorliegende Anmeldung betrifft neue Difluorphenol-Derivate, Verfahren zu ihrer Herstellung, ihre Verwendung zur Behandlung und/oder Prophylaxe von Krankheiten sowie ihre Verwendung zur Herstellung von Arzneimitteln zur Behandlung und/oder Prophylaxe von Krankheiten, insbesondere zur Behandlung und/oder Prävention kardiovaskulärer Erkrankungen.
(EN)
The present application relates to new difluorophenol derivatives, methods for preparing the same, their use for the treatment and/or prevention of diseases, and their use for producing medicaments for the treatment and/or prevention of diseases, in particular for treating and/or preventing cardiovascular diseases.
(FR)
L'invention concerne de nouveaux dérivés de difluorophénol, des procédés pour les produire et leur utilisation pour le traitement et/ou la prophylaxie de maladies, ainsi que leur utilisation pour réaliser des médicaments destinés au traitement et/ou à la prophylaxie de maladies, notamment le traitement et/ou la prévention de maladies cardio-vasculaires.
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