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1. WO2007041641 - METHODS OF REDUCING THE PRODUCTION OF REACTIVE OXYGEN SPECIES AND METHODS OF SCREENING OR IDENTIFYING COMPOUNDS AND COMPOSITIONS THAT REDUCE THE PRODUCTION OF REACTIVE OXYGEN SPECIES

Publication Number WO/2007/041641
Publication Date 12.04.2007
International Application No. PCT/US2006/038854
International Filing Date 03.10.2006
IPC
G01N 33/50 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
A61P 3/04 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3Drugs for disorders of the metabolism
04Anorexiants; Antiobesity agents
CPC
A61K 31/355
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
335having oxygen as the only ring hetero atom, e.g. fungichromin
35having six-membered rings with one oxygen as the only ring hetero atom
352condensed with carbocyclic rings, e.g. cannabinols, methantheline
3533,4-Dihydrobenzopyrans, e.g. chroman, catechin
355Tocopherols, e.g. vitamin E
A61K 33/06
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
33Medicinal preparations containing inorganic active ingredients
06Aluminium, calcium or magnesium; Compounds thereof ; , e.g. clay
A61K 45/06
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
45Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
A61P 3/04
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3Drugs for disorders of the metabolism
04Anorexiants; Antiobesity agents
A61P 39/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
39General protective or antinoxious agents
G01N 2800/044
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
2800Detection or diagnosis of diseases
04Endocrine or metabolic disorders
044Hyperlipemia or hypolipemia, e.g. dyslipidaemia, obesity
Applicants
  • UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION [US]/[US] (AllExceptUS)
  • ZEMEL, Michael, B. [US]/[US] (UsOnly)
Inventors
  • ZEMEL, Michael, B.
Agents
  • EISENSCHENK, Frank, C.
Priority Data
60/723,04203.10.2005US
60/787,81931.03.2006US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) METHODS OF REDUCING THE PRODUCTION OF REACTIVE OXYGEN SPECIES AND METHODS OF SCREENING OR IDENTIFYING COMPOUNDS AND COMPOSITIONS THAT REDUCE THE PRODUCTION OF REACTIVE OXYGEN SPECIES
(FR) PROCEDES DE REDUCTION DE LA PRODUCTION D'ESPECES D'OXYGENE REACTIVES ET PROCEDES DE CRIBLAGE ET D'IDENTIFICATION DE COMPOSES ET DE COMPOSITIONS REDUISANT LA PRODUCTION D'ESPECES D'OXYGENE REACTIVES
Abstract
(EN)
The subject application provides methods of identifying compounds, combinations of compounds, compositions, and/or combinations of compositions that are suitable for reducing the production of reactive oxygen species (ROS) in an individual with the proviso that said compound, combination of compounds, composition, or combination of compositions is not a dietary material containing calcium or dietary calcium. Also provided in the subject application are methods of treating diseases or disorders associated with ROS production and methods of reducing ROS production in an individual with the proviso that said compound, combination of compounds, composition, or combination of compositions is not a dietary material containing calcium or dietary calcium.
(FR)
L'invention concerne des procédés permettant d'identifier des composés, des combinaisons de composés, des compositions et/ou des combinaisons de compositions appropriés pour réduire la production d'espèces d'oxygène réactives (ROS) chez un individu, pour autant que lesdits composé, combinaisons de composés, compositions et/ou combinaisons de compositions ne soient pas une matière alimentaire contenant du calcium ou du calcium alimentaire. L'invention concerne également des procédés permettant de traiter des maladies ou troubles associés à la production de ROS, ainsi que des procédés permettant de réduire la production de ROS chez un individu pour autant que lesdits composé, combinaisons de composés, composition et/ou combinaisons de compositions ne soient pas une matière alimentaire contenant du calcium ou du calcium alimentaire.
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