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1. WO2007035721 - ULTRASOUND METHOD TO OPEN BLOOD BRAIN BARRIER

Publication Number WO/2007/035721
Publication Date 29.03.2007
International Application No. PCT/US2006/036460
International Filing Date 19.09.2006
IPC
A61B 8/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
8Diagnosis using ultrasonic, sonic or infrasonic waves
CPC
A61B 8/0816
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
8Diagnosis using ultrasonic, sonic or infrasonic waves
08Detecting organic movements or changes, e.g. tumours, cysts, swellings
0808for diagnosis of the brain
0816using echo-encephalography
A61M 37/0092
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY
37Other apparatus for introducing media into the body
0092using ultrasonic, sonic or infrasonic vibrations, e.g. phonophoresis
Applicants
  • THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK [US]/[US] (AllExceptUS)
  • KONOFAGOU, Elisa, E. [GR]/[US] (UsOnly)
  • CHOI, James, J. [US]/[US] (UsOnly)
  • PERNOT, Mathieu [FR]/[FR] (UsOnly)
  • SMALL, Scott, A. [US]/[US] (UsOnly)
Inventors
  • KONOFAGOU, Elisa, E.
  • CHOI, James, J.
  • PERNOT, Mathieu
  • SMALL, Scott, A.
Agents
  • RAGUSA, Paul, A.
Priority Data
60/718,58219.09.2005US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) ULTRASOUND METHOD TO OPEN BLOOD BRAIN BARRIER
(FR) SYSTEMES ET PROCEDES PERMETTANT D'OUVRIR LA BARRIERE SANG-CERVEAU D'UN SUJET PAR ULTRASONS
Abstract
(EN)
A system and method for opening the blood-brain barrier in the brain of a subject is disclosed. In some embodiments, a region of the brain of a subject is targeted for opening; and a focused ultrasound beam is applied through the skull of the subject to the targeted region to open the blood-brain barrier in the brain of the subject.
(FR)
L'invention concerne un systeme et un procédé permettant d'ouvrir la barrière sang-cerveau du cerveau d'un sujet. Dans certains modes de réalisation, une région du cerveau d'un sujet est ciblée pour être ouverte; et un faisceau ultrasonore focalisé est appliqué à travers le squelette céphalique du sujet sur la région ciblée afin d'ouvrir la barrière sang-cerveau du cerveau du sujet.
Also published as
US12077612
Latest bibliographic data on file with the International Bureau