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1. WO2007035530 - ANCESTRAL DENGUE VIRUS ENVELOPE PROTEIN SEQUENCE

Publication Number WO/2007/035530
Publication Date 29.03.2007
International Application No. PCT/US2006/036107
International Filing Date 15.09.2006
IPC
A61K 39/12 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
12Viral antigens
CPC
C07K 14/005
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
005from viruses
C12N 2710/14143
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
2710dsDNA Viruses
00011dsDNA Viruses
14011Baculoviridae
14111Nucleopolyhedrovirus, e.g. autographa californica nucleopolyhedrovirus
14141Use of virus, viral particle or viral elements as a vector
14143viral genome or elements thereof as genetic vector
C12N 2770/24122
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
2770ssRNA Viruses positive-sense
00011ssRNA Viruses positive-sense
24011Flaviviridae
24111Flavivirus, e.g. yellow fever virus, dengue, JEV
24122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Applicants
  • SAINT LOUIS UNIVERSITY [US]/[US] (AllExceptUS)
  • FAN, Xiaofeng [CN]/[US] (UsOnly)
Inventors
  • FAN, Xiaofeng
Agents
  • ZAHNER, Joseph
Priority Data
60/718,17816.09.2005US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) ANCESTRAL DENGUE VIRUS ENVELOPE PROTEIN SEQUENCE
(FR) SEQUENCE PROTEIQUE DE L'ENVELOPPE DU VIRUS DE LA DENGUE ANCESTRAL
Abstract
(EN)
Disclosed is a dengue virus envelope protein sequence derived via ascertainment of a most recent common ancestor of the three dengue serotype variants, DENV-I, DENV-2, DENV-3 and DENV-4. This synthetic dengue virus envelope protein can be used as a tetravalent vaccine in the preventinon of dengue fever, dengue hemorrhagic fever and dengue septic shock.
(FR)
L'invention concerne une séquence protéique de l'enveloppe du virus de la dengue dérivée par vérification d'un ancêtre commun le plus récent des trois variants des sérotypes de la dengue : DENV-I, DENV-2, DENV-3 et DENV-4. Cette protéine de l'enveloppe du virus de la dengue synthétique peut être utilisé comme vaccin tétravalent dans la prévention de la dengue, de la dengue hémorragique et du choc septique de la dengue.
Also published as
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