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1. WO2007028167 - DEVICES FOR TRANSCUTANEOUS DELIVERY OF VACCINES AND TRANSDERMAL DELIVERY OF DRUGS AND USES THEREOF

Publication Number WO/2007/028167
Publication Date 08.03.2007
International Application No. PCT/US2006/034620
International Filing Date 05.09.2006
IPC
A61M 35/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
35Devices for applying media, e.g. remedies, on the human body
CPC
A61B 17/20
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
17Surgical instruments, devices or methods, e.g. tourniquets
20for vaccinating or cleaning the skin previous to the vaccination
A61B 17/205
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
17Surgical instruments, devices or methods, e.g. tourniquets
20for vaccinating or cleaning the skin previous to the vaccination
205Vaccinating by means of needles or other puncturing devices
A61B 2017/00115
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
17Surgical instruments, devices or methods, e.g. tourniquets
00017Electrical control of surgical instruments
00115with audible or visual output
A61B 2017/00761
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
17Surgical instruments, devices or methods, e.g. tourniquets
00743Type of operation; Specification of treatment sites
00747Dermatology
00761Removing layer of skin tissue, e.g. wrinkles, scars or cancerous tissue
A61B 2090/065
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
90Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
06Measuring instruments not otherwise provided for
064for measuring force, pressure or mechanical tension
065for measuring contact or contact pressure
A61M 2037/0023
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY
37Other apparatus for introducing media into the body
0015by using microneedles
0023Drug applicators using microneedles
Applicants
  • IOMAI CORPORATION [US]/[US] (AllExceptUS)
  • GLENN, Gregory, M. [US]/[US] (UsOnly)
  • DOERKSEN, Kyle, J. [CA]/[US] (UsOnly)
  • ELLINGSWORTH, Larry, R. [US]/[US] (UsOnly)
  • EPPERSON, Diane, E. [US]/[US] (UsOnly)
  • FRERICHS, David [US]/[US] (UsOnly)
  • HAMER, Mervyn, L. [US]/[US] (UsOnly)
  • HENNINGSGAARD, Aaron, A. [US]/[US] (UsOnly)
  • INOUYE, Matthew, D. [US]/[US] (UsOnly)
  • JAMES, Adrian, B. [US]/[US] (UsOnly)
  • KAPLAN, Jonathan, I. [US]/[US] (UsOnly)
  • LAI, John, W. [US]/[US] (UsOnly)
  • LISTER, Robert, I. [GB]/[GB] (UsOnly)
  • LUBENSKY, David, A. [US]/[US] (UsOnly)
  • MACDONALD, Peter, S. [US]/[US] (UsOnly)
  • MADSEN, Sally, H. [US]/[US] (UsOnly)
  • MASON, Brian, J. [US]/[US] (UsOnly)
  • MCELHANEY, Christine, W. [US]/[US] (UsOnly)
  • MOHRI, Lionel [US]/[US] (UsOnly)
  • PIGLIACAMPO, Anthony, C. [US]/[US] (UsOnly)
  • ROMERO, Gina, L. [US]/[US] (UsOnly)
  • STEEVES, Charles, F., III [CA]/[CA] (UsOnly)
  • VILLAR, Christina, P. [US]/[US] (UsOnly)
  • YU, Jianmei [US]/[US] (UsOnly)
Inventors
  • GLENN, Gregory, M.
  • DOERKSEN, Kyle, J.
  • ELLINGSWORTH, Larry, R.
  • EPPERSON, Diane, E.
  • FRERICHS, David
  • HAMER, Mervyn, L.
  • HENNINGSGAARD, Aaron, A.
  • INOUYE, Matthew, D.
  • JAMES, Adrian, B.
  • KAPLAN, Jonathan, I.
  • LAI, John, W.
  • LISTER, Robert, I.
  • LUBENSKY, David, A.
  • MACDONALD, Peter, S.
  • MADSEN, Sally, H.
  • MASON, Brian, J.
  • MCELHANEY, Christine, W.
  • MOHRI, Lionel
  • PIGLIACAMPO, Anthony, C.
  • ROMERO, Gina, L.
  • STEEVES, Charles, F., III
  • VILLAR, Christina, P.
  • YU, Jianmei
Agents
  • CLARK, Paul, T.
Priority Data
60/714,07302.09.2005US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) DEVICES FOR TRANSCUTANEOUS DELIVERY OF VACCINES AND TRANSDERMAL DELIVERY OF DRUGS AND USES THEREOF
(FR) DISPOSITIFS D’ADMINISTRATION TRANSCUTANÉE DE VACCINS ET D'ADMINISTRATION TRANSDERMIQUE DE MÉDICAMENTS ET UTILISATIONS IDOINES
Abstract
(EN)
The invention provides devices for the disruption of one or more layers of skin and methods of their use to administer therapeutic agents, e.g., antigens or drugs. The devices are designed to disrupt a defined area of skin. The defined area can approximate the area that a patch or other suitable vehicle for therapeutic agent, e.g., drug or vaccine, delivery is designed to contact. Exemplary devices employ a mask to define the area to be disrupted. Other devices disrupt a defined area by rotating in place. For devices that employ a mask that is secured to the skin, the invention provides methods of disrupting the stratum corneum by first securing the mask to the skin and then disrupting the skin. For rotating devices, the disrupting member is simply placed against the skin and actuated to effect disruption.
(FR)
L'invention concerne des dispositifs de percement d’une ou de plusieurs couches de peau et des procédés d’utilisation de ceux-ci pour administrer des agents thérapeutiques, par exemple, des antigènes ou des médicaments. Les dispositifs sont conçus pour percer une zone de peau définie. La zone définie peut correspondre à la zone avec laquelle un patch ou autre véhicule adéquat pour l'administration d'un agent thérapeutique, par exemple un médicament ou un vaccin, doit entrer en contact. Des dispositifs exemplaires emploient un masque pour définir la zone à percer. D’autres dispositifs percent une surface définie en tournant sur place. Pour les dispositifs employant un masque fixé à la peau, on propose des procédés de percement de la strate de cornée en fixant d’abord le masque à la peau, avant de percer la peau. Pour les dispositifs rotatifs, l’élément de percement est simplement placé contre la peau et actionné pour réaliser le percement.
Latest bibliographic data on file with the International Bureau