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Machine translation
1. (WO2007022478) TRANSCRIPTION FACTORS IN NEURONAL DENDRITES-DENDRITIC PROTEIN SYNTHESIS AND CELL DEATH
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2007/022478    International Application No.:    PCT/US2006/032513
Publication Date: 22.02.2007 International Filing Date: 17.08.2006
IPC:
A61K 31/70 (2006.01), A01N 63/00 (2006.01), C12N 15/00 (2006.01), C12N 5/00 (2006.01), C12N 15/63 (2006.01)
Applicants: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA CENTER FOR TECHNOLOGY TRANSFER [US/US]; Suite 200, 3160 Chestnut Street, Philadelphia, PA 19104-6283 (US) (For All Designated States Except US).
EBERWINE, James, H. [US/US]; (US) (For US Only).
BARRETT, Lindy, E. [US/US]; (US) (For US Only)
Inventors: EBERWINE, James, H.; (US).
BARRETT, Lindy, E.; (US)
Agent: DOYLE, Kathryn; DRINKER BIDDLE & REATH LLP, One Logan Square, 18th and Cherry Streets, Philadelphia, PA 19103 (US)
Priority Data:
60/708,981 17.08.2005 US
60/736,993 15.11.2005 US
Title (EN) TRANSCRIPTION FACTORS IN NEURONAL DENDRITES-DENDRITIC PROTEIN SYNTHESIS AND CELL DEATH
(FR) FACTEURS DE TRANSCRIPTION DANS LA SYNTHÈSE DENDRITES-PROTÉINE DENDRITIQUE NEURALE ET MORT CELLULAIRE
Abstract: front page image
(EN)The present invention relates to methods of altering the competence of a dendrite and/or the viability of a neuron. The present invention also provides methods of altering the ATP levels in a neuron, methods of isolating at least one protein of a mitochondrial permeability transition pore complex, methods of introducing an RNA into a neuron, methods of translating an RNA in a dendrite, methods of monitoring risk of neurodegeneration of a neuron, and methods of treatment for neurodegenerative diseases.
(FR)La présente invention concerne des méthodes pour modifier la compétence d'un dendrite et/ou la viabilité d'un neurone. Elle concerne aussi des méthodes pour changer les niveaux d’ATP dans un neurone, des méthodes pour isoler au moins une protéine d'un complexe de pore de transition de perméabilité mitochondrial, des méthodes pour introduire un ARN dans un neurone, des méthodes pour traduire un ARN dans un dendrite, des méthodes pour surveiller le risque de neurodégénération d'un neurone et des méthodes pour traiter des maladies neurodégénératives.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)