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Machine translation
1. (WO2007021756) METHODS FOR CHARACTERIZING BIOLOGICAL MOLECULE MODULATORS
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2007/021756 International Application No.: PCT/US2006/031055
Publication Date: 22.02.2007 International Filing Date: 10.08.2006
IPC:
C12N 15/09 (2006.01) ,C12Q 1/00 (2006.01) ,G01N 33/53 (2006.01)
Applicants: PATEL, Mehul[US/US]; US (UsOnly)
SCHMIDT, Dawn, M.[US/US]; US (UsOnly)
THRALL, Sara, H.[US/US]; US (UsOnly)
TEW, David, G.[US/GB]; GB (UsOnly)
EKSIGENT TECHNOLOGIES, LLC[US/US]; 5875 Arnold Road, Suite 300 Dublin, CA 94568, US (AllExceptUS)
Inventors: PATEL, Mehul; US
SCHMIDT, Dawn, M.; US
THRALL, Sara, H.; US
TEW, David, G.; GB
Agent: FEDRICK, Michael, F. ; Sheldon Mak Rose & Anderson PC 100 East Corson Street 3rd Floor Pasadena, CA 91103-3842, US
Priority Data:
60/707,32811.08.2005US
Title (EN) METHODS FOR CHARACTERIZING BIOLOGICAL MOLECULE MODULATORS
(FR) METHODES DE CARACTERISATION DE MODULATEURS DE MOLECULES BIOLOGIQUES
Abstract: front page image
(EN) Methods for characterizing a biochemical reaction and analysis of reaction products by establishing continuously variable concentration gradients of one or more reagents of the biochemical reaction are provided. Methods for determining mechanism of inhibition or activation, potency of inhibition or activation, or both of an enzyme inhibitor or activator, respectively, are also provided. The continuously variable concentration gradients can be established in a microfluidic chip.
(FR) Cette invention concerne des méthodes de caractérisation d'une réaction biochimique et d'analyse de produits de réaction, consistant à établir des gradients de concentration à variation continue d'un ou de plusieurs réactifs de la réaction biochimique. Sont également décrites des méthodes de détermination du mécanismes d'inhibition ou d'activation, voire des deux, d'un inhibiteur ou d'un activateur d'enzymes, respectivement. Les gradients de concentration à variation continue peuvent être établis dans une puce microfluidique.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)