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Pub. No.:    WO/2007/020521    International Application No.:    PCT/IB2006/002234
Publication Date: 22.02.2007 International Filing Date: 16.08.2006
C07D 471/04 (2006.01), A61K 31/495 (2006.01), A61P 9/00 (2006.01)
Applicants: PHARMACIA & UPJOHN COMPANY LLC [US/US]; 7000 Portage Road, Kalamazoo, MI 49001-0199 (US) (For All Designated States Except US).
BROWN, David, Louis [US/US]; (US) (For US Only).
OWEN, Dafydd, Rhys [GB/GB]; (GB) (For US Only).
PHILLIPS, Christopher [GB/GB]; (GB) (For US Only).
PALMER, Michael, John [GB/GB]; (GB) (For US Only).
BELL, Andrew, Simon [GB/GB]; (GB) (For US Only).
FRESKOS, John, Nicholas [US/US]; (US) (For US Only).
FOBJAN, Yvette, Marlene [US/US]; (US) (For US Only).
WALKER, John, Keith [US/US]; (US) (For US Only).
HUGHES, Robert, Craig [US/US]; (US) (For US Only).
JACOBSEN, Eric, Jon [US/US]; (US) (For US Only).
TOLLEFSON, Michael, Brent [US/US]; (US) (For US Only).
BROWN, David, Graham [GB/GB]; (GB) (For US Only).
MISCHKE, Brent, Virgil [US/US]; (US) (For US Only).
MOLYNEAUX, John, Major [US/US]; (US) (For US Only)
Inventors: BROWN, David, Louis; (US).
OWEN, Dafydd, Rhys; (GB).
PHILLIPS, Christopher; (GB).
PALMER, Michael, John; (GB).
BELL, Andrew, Simon; (GB).
FRESKOS, John, Nicholas; (US).
FOBJAN, Yvette, Marlene; (US).
WALKER, John, Keith; (US).
HUGHES, Robert, Craig; (US).
JACOBSEN, Eric, Jon; (US).
TOLLEFSON, Michael, Brent; (US).
BROWN, David, Graham; (GB).
MISCHKE, Brent, Virgil; (US).
MOLYNEAUX, John, Major; (US)
Agent: FULLER, Grover, F., Jr.; Pfizer Inc., 150 East 42nd Street, New York, NY 10017-5612 (US)
Priority Data:
60/708,516 16.08.2005 US
Abstract: front page image
(EN)Compounds, and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula I: wherein R2, R3, R4, X6, Y6, R6, and R8 are as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, synthetic methods, and intermediates are also disclosed.
(FR)L'invention concerne des composés et des sels pharmaceutiquement acceptables de ceux-ci. Ces composés ont la structure représentée par formule I, dans laquelle R2, R3, R4, X6, Y6, R6 et R8 sont tels que définis dans le descriptif. Des compositions pharmaceutiques correspondantes, des méthodes de traitement, des procédés de synthèse et des produits intermédiaires sont également décrits.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)