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1. (WO2007019618) PHROPHYLACTIC AND/OR THERAPEUTIC METHOD FOR TREATMENT OF AUTOIMMUNE DISEASE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2007/019618    International Application No.:    PCT/AU2006/001163
Publication Date: 22.02.2007 International Filing Date: 14.08.2006
IPC:
A61K 39/395 (2006.01), A61K 38/00 (2006.01), A61P 3/08 (2006.01), A61P 3/10 (2006.01), A61P 37/00 (2006.01), A61P 37/02 (2006.01), A61P 37/06 (2006.01)
Applicants: GARVAN INSTITUTE OF MEDICAL RESEARCH [AU/AU]; C/- St Vincent's Hospital, 384 Victoria Street, Darlinghurst, New South Wales 2010 (AU) (For All Designated States Except US).
GREY, Shane [AU/AU]; (AU) (For US Only)
Inventors: GREY, Shane; (AU)
Agent: FB RICE & CO; Level 23, 44 Market Street, Sydney, New South Wales 2000 (AU)
Priority Data:
60/707,803 12.08.2005 US
Title (EN) PHROPHYLACTIC AND/OR THERAPEUTIC METHOD FOR TREATMENT OF AUTOIMMUNE DISEASE
(FR) PROCÉDÉ THÉRAPEUTIQUE ET/OU PHROPYLACTIQUE POUR LE TRAITEMENT D’UNE MALADIE AUTO-IMMUNE
Abstract: front page image
(EN)The present invention provides therapeutic and/or prophylactic method comprising administering to a subject an amount of a composition sufficient to reduce or deplete antibody producing cells and/or prevent expansion of said cells in a tissue or organ of a subject suffering from T cell mediated autoimmune disease e.g., type 1 diabetes, or at risk of suffering from said disease, preferably wherein the composition is administered immediately prior to or concomitant with an autoimmune response. The present invention also provides the use of said composition in the manufacture of a medicament for the treatment and/or prevention of T cell mediated autoimmune disease. The present invention also provides said composition for use in the treatment and/or prevention of T cell mediated autoimmune disease.
(FR)La présente invention concerne un procédé thérapeutique et/ou prophylactique consistant en l’administration à un patient d’une quantité de composition suffisante pour réduire ou diminuer des cellules productrices d’anticorps et/ou empêcher l’expansion desdites cellules dans le tissu ou l’organe d’un patient souffrant de la maladie auto-immune à médiation par lymphocytes T, diabète de type 1, ou à risque de souffrir de cette maladie, dans lequel la composition est de préférence administrée immédiatement avant ou de manière concomitante avec une réponse auto-immune. La présente invention fournit aussi l’utilisation de ladite composition dans la fabrication d’un médicament pour le traitement et/ou la prévention de la maladie auto-immune à médiation par lymphocytes T. La présente invention fournit aussi ladite composition à utiliser pour le traitement et/ou la prévention de la maladie auto-immune à médiation par lymphocytes T.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)