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1. (WO2007017145) GSK-3 INHIBITORS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2007/017145    International Application No.:    PCT/EP2006/007520
Publication Date: 15.02.2007 International Filing Date: 28.07.2006
Chapter 2 Demand Filed:    29.05.2007    
IPC:
A61K 31/17 (2006.01), A61K 31/36 (2006.01), A61P 25/28 (2006.01), A61P 3/10 (2006.01), A61P 25/24 (2006.01), A61P 25/00 (2006.01), A61P 9/10 (2006.01), C07D 317/66 (2006.01)
Applicants: NEUROPHARMA, S.A. [ES/ES]; Avenida De La Industria, 52, E-28760 Tres Cantos - Madrid (ES) (For All Designated States Except US).
MARTÍNEZ GIL, Ana [ES/ES]; (ES) (For US Only).
MEDINA PADILLA, Miguel [ES/ES]; (ES) (For US Only).
ALONSO CASCÓN, Mercedes [ES/ES]; (ES) (For US Only).
FUERTES HUERTA, Ana [ES/ES]; (ES) (For US Only).
NAVARRO RICO, María Luisa [ES/ES]; (ES) (For US Only).
PÉREZ PUERTO, María José [ES/ES]; (ES) (For US Only).
CASTRO MORERA, Ana [ES/ES]; (ES) (For US Only).
MARTÍN APARICIO, Ester [ES/ES]; (ES) (For US Only)
Inventors: MARTÍNEZ GIL, Ana; (ES).
MEDINA PADILLA, Miguel; (ES).
ALONSO CASCÓN, Mercedes; (ES).
FUERTES HUERTA, Ana; (ES).
NAVARRO RICO, María Luisa; (ES).
PÉREZ PUERTO, María José; (ES).
CASTRO MORERA, Ana; (ES).
MARTÍN APARICIO, Ester; (ES)
Agent: ARIAS SANZ, Juan; ABG Patentes, S.L., Avenida de Burgos, 16D, Edificio Euromor, E-28036 Madrid (ES)
Priority Data:
05380176.7 29.07.2005 EP
Title (EN) GSK-3 INHIBITORS
(FR) INHIBITEURS DE LA GSK-3
Abstract: front page image
(EN)The invention relates to urea derivatives of formula (I) as inhibitors of glycogen synthase kinase 3ß, GSK-3, to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use for the treatment and or prophylaxis of a disease in which GSK-3 is involved, such as Alzheimer's disease or non-insulin dependent diabetes mellitus.
(FR)L'invention concerne des dérivés d'urée représentés par la formule (I), utilisés comme inhibiteurs de la glycogène synthase kinase 3ß, GSK-3, des procédés permettant de préparer ces composés, des compositions pharmaceutiques contenant ces composés, et l'utilisation de ces composés pour le traitement et/ou la prévention d'une maladie faisant intervenir la GSK 3, telle que la maladie d'Alzheimer ou le diabète non insulinodépendant.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)