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Machine translation
1. (WO2007016566) PRODUCTION OF REPROGRAMMED CELLS WITH RESTORED POTENTIAL
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2007/016566    International Application No.:    PCT/US2006/029944
Publication Date: 08.02.2007 International Filing Date: 01.08.2006
IPC:
C12N 15/09 (2006.01)
Applicants: NUPOTENTIAL, LLC [US/US]; 7415 Valley View Road, Verona, WI 53593 (US) (For All Designated States Except US).
EILERTSEN, Kenneth, J. [US/US]; (US) (For US Only)
Inventors: EILERTSEN, Kenneth, J.; (US)
Agent: SARA, Charles, S.; DEWITT ROSS & STEVENS S.C., 8000 Excelsior Drive, Suite 401, Madison, WI 53717-1914 (US)
Priority Data:
60/704,465 01.08.2005 US
Title (EN) PRODUCTION OF REPROGRAMMED CELLS WITH RESTORED POTENTIAL
(FR) PRODUCTION DE CELLULES REPROGRAMMEES PRESENTANT UN POTENTIEL REGENERE
Abstract: front page image
(EN)A method for treating cells and/or nuclear transfer units and/or stem cells in culture with such compounds, individually or in combinations, is described. The method results in a globally hypomethylated genome and a restoration of cell differentiation and/or developmental potential, or potentiality. In addition, a method for the in vitro production of reprogrammed cells which have had differentiation potential (totipotential, pluripotential, or multipotential) restored by demethylating the genome is described.
(FR)L'invention concerne un procédé de traitement de cellules et/ou d'unités de transfert nucléaire et/ou de cellules souches en culture avec des composés utilisés seuls ou combinés. Le procédé produit un génome globalement hypométhylé et un rétablissement de la différenciation cellulaire et/ou du pouvoir de développement ou de la potentialité. L'invention concerne également un procédé de production in vitro de cellules reprogrammées dont le pouvoir de différenciation (totipotence, pluripotence ou multipotence) a été rétabli par déméthylation du génome.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)