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1. (WO2007016419) METHODS AND COMPOSITIONS FOR REDUCING SKIN DAMAGE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2007/016419    International Application No.:    PCT/US2006/029581
Publication Date: 08.02.2007 International Filing Date: 28.07.2006
IPC:
A61K 8/02 (2006.01), A61K 8/49 (2006.01), A61K 31/495 (2006.01)
Applicants: THE GENERAL HOSPITAL CORPORATION [US/US]; 55 Fruit Street, Boston, Massachusetts 02114 (US) (For All Designated States Except US).
FUJII, Seishiro [JP/US]; (US) (For US Only).
DOTTO, Gian Paolo [US/US]; (US) (For US Only)
Inventors: FUJII, Seishiro; (US).
DOTTO, Gian Paolo; (US)
Agent: TABTIANG, Ramon; Fish & Richardson P.C., PO Box 1022, Minneapolis, MN 55440-1022 (US)
Priority Data:
60/703,982 29.07.2005 US
Title (EN) METHODS AND COMPOSITIONS FOR REDUCING SKIN DAMAGE
(FR) PRECEDES ET COMPOSITIONS POUR REDUIRE LES LESIONS CUTANEES
Abstract: front page image
(EN)The Notch signal transduction pathway has been identified as a target for screening and treatment methods for the prevention and/or reduction of short- and long-term UVB-induced skin damage, e.g., the prevention and/or reduction of UVB-induced wrinkles. The invention thus features screening and treatment methods for prevention or reduction of UVB-induced sin damage, and related compositions, e.g., cosmetic compositions.
(FR)L'invention porte sur le mécanisme d'action de transduction du signal Notch qui a été identifié comme cible dans des méthodes de recherche systématique et de traitement utilisées dans la prévention et/ou la réduction de lésions cutanées induites à court et long terme par les rayons UVB, par exemple, la prévention et/ou la réduction des rides induites par les rayons UVB. L'invention porte également sur des méthodes de recherche systématique et de traitement utilisées dans la prévention ou la réduction de lésions cutanées induites par les rayons UVB, ainsi que sur des compositions correspondantes telles que des compositions cosmétiques.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)