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Pub. No.:    WO/2007/015929    International Application No.:    PCT/US2006/028169
Publication Date: 08.02.2007 International Filing Date: 20.07.2006
A01N 57/00 (2006.01), A01N 43/02 (2006.01)
Applicants: UNIVERSITY OF TOLEDO [US/US]; A University Instrumentality of the State of Ohio, 2801 W. Bancroft Avenue, Toledo, OH 43606 (US) (For All Designated States Except US).
TILLEKERATNE, Viranga [US/US]; (US) (For US Only).
HUDSON, Richard, A. [US/US]; (US) (For US Only).
ALHAMADSHEH, Mamoun [JO/US]; (US) (For US Only)
Inventors: TILLEKERATNE, Viranga; (US).
HUDSON, Richard, A.; (US).
Agent: MARTINEAU, Catherine, B.; MacMillan, Sobanski & Todd, LLC, One Maritime Plaza, Fifth Floor, 720 Water Street, Toledo, OH 43604 (US)
Priority Data:
60/702,936 27.07.2005 US
Abstract: front page image
(EN)Epothilone analogues include a molecular scaffold which holds at least one segment of epothilone in a predetermined orientation and which rigidities a region between the macrolactone ring and the aromatic side-chain.
(FR)L'invention concerne des analogues d'épothilone comprenant un échafaudage moléculaire qui maintient au moins un segment d'épothilone dans une orientation prédéterminée et qui rigidifie une zone entre le cycle macrolactone et la chaîne latérale aromatique.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)