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1. (WO2007015926) MULTIPARAMETER FLOW CYTOMETRIC CYTOMETRIC CYTOTOXICITY SYSTEMS, METHODS, COMPOSITIONS AND KITS FOR EVALUATING THE SUSCEPTIBILITY OF CANCER
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2007/015926    International Application No.:    PCT/US2006/028159
Publication Date: 08.02.2007 International Filing Date: 21.07.2006
IPC:
G01N 33/574 (2006.01)
Applicants: OREGON HEALTH AND SCIENCE UNIVERSITY [US/US]; 2525 S.W. First Avenue, Suite 120, Portlland, OR 97201 (US) (For All Designated States Except US).
HUANG, James, Z. [US/US]; (US) (For US Only).
ZHONG, Yanping [CN/US]; (US) (For US Only).
BAKKE, Antony [US/US]; (US) (For US Only)
Inventors: HUANG, James, Z.; (US).
ZHONG, Yanping; (US).
BAKKE, Antony; (US)
Agent: MYLES, Gary, M.; Darby & Darby P.C., P.O. Box 770, Church Street Station, New York, NY 10008-0770 (US)
Priority Data:
60/702,438 25.07.2005 US
Title (EN) MULTIPARAMETER FLOW CYTOMETRIC CYTOMETRIC CYTOTOXICITY SYSTEMS, METHODS, COMPOSITIONS AND KITS FOR EVALUATING THE SUSCEPTIBILITY OF CANCER
(FR) SYSTEMES ET PROCEDES MULTIPARAMETRE DE CYTOTOXICITE A CYTOMETRIE DE FLUX, COMPOSITIONS ET KITS D'EVALUATION DE LA SUSCEPTIBILITE DE CELLULES CANCEREUSES A UNE MODALITE DE TRAITEMENT
Abstract: front page image
(EN)Provided are multiparameter flow cytometric cytotoxicity systems, methods, compositions, and kits for assessing whether one or more cancer cell(s) in a patient sample are susceptible to a chemotherapeutic or other cancer treatment modality. The present invention will find utility in the development of personalized therapeutic strategies for selection of appropriate chemotherapeutic or other treatment modalities based on the drug sensitivity and resistance profiles of cancer cells from individual patients.
(FR)L'invention concerne des systèmes et des méthodes multiparamètre de cytotoxicité à cytométrie de flux ainsi que des compositions et des kits permettant d'apprécier si une ou plusieurs cellules cancéreuses d'un échantillon prélevé sur un patient présentent une susceptibilité à un mode de chimiothérapie ou autre mode de traitement du cancer. La présente invention convient pour l'élaboration de stratégies thérapeutiques personnalisées permettant de choisir des modalités chimiothérapeutiques et autres à partir des profils de sensibilité à un médicament et de résistance de cellules cancéreuses de patients.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)