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Machine translation
1. (WO2007015923) BENZIMIDAZOLES USEFUL AS INHIBITORS OF PROTEIN KINASES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2007/015923    International Application No.:    PCT/US2006/028149
Publication Date: 08.02.2007 International Filing Date: 21.07.2006
IPC:
C07D 403/04 (2006.01), C07D 401/14 (2006.01), C07D 403/14 (2006.01), A61K 31/506 (2006.01), A61K 31/4439 (2006.01), A61K 31/55 (2006.01), A61K 31/551 (2006.01), A61P 35/00 (2006.01)
Applicants: VERTEX PHARMACEUTICALS INCORPORATED [US/US]; 130 Waverly Street, Cambridge, MA 02139 (US) (For All Designated States Except US).
BINCH, Hayley [GB/GB]; (GB) (For US Only).
EVERITT, Simon [GB/GB]; (GB) (For US Only).
MORTIMORE, Michael [GB/GB]; (GB) (For US Only).
ROBINSON, Daniel [GB/GB]; (GB) (For US Only).
STAMOS, Dean [US/US]; (US) (For US Only)
Inventors: BINCH, Hayley; (GB).
EVERITT, Simon; (GB).
MORTIMORE, Michael; (GB).
ROBINSON, Daniel; (GB).
STAMOS, Dean; (US)
Agent: CHE, Jennifer, G.; Vertex Pharmaceuticals Incorparated, 130 Waverly Street, Cambridge, MA 02139 (US)
Priority Data:
60/702,399 26.07.2005 US
Title (EN) BENZIMIDAZOLES USEFUL AS INHIBITORS OF PROTEIN KINASES
(FR) BENZIMIDAZOLES UTILES COMME INHIBITEURS DE PROTEINES KINASES
Abstract: front page image
(EN)The present invention relates to compounds useful as inhibitors of Aurora, FLT-3, or PDKl protein kinase. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing compounds of the invention.
(FR)La présente invention concerne des composé utiles comme inhibiteurs d'Aurora, de FLT-3 ou de la protéine kinase PDK1. L'invention concerne également des compositions pharmaceutiquement acceptables comprenant ces composés ainsi que des méthodes d'utilisation de ces compositions dans le traitement de maladies, d'affections ou de troubles divers. L'invention se rapporte en outre à des procédés de préparation des composés susmentionnés.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)