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Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2007/015870    International Application No.:    PCT/US2006/027875
Publication Date: 08.02.2007 International Filing Date: 18.07.2006
Chapter 2 Demand Filed:    22.05.2007    
C07D 401/14 (2006.01), A61K 31/506 (2006.01), A61P 35/00 (2006.01)
Applicants: NOVARTIS AG [CH/CH]; Lichtstrasse 35, CH-4056 Basel (CH) (AE, AG, AL, AM, AU, AZ, BA, BB, BE, BF, BG, BJ, BR, BW, BY, BZ, CA, CF, CG, CH, CI, CM, CN, CO, CR, CU, CY, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, FR, GA, GB, GD, GE, GH, GM, GN, GQ, GR, GW, HN, HR, HU, ID, IE, IL, IN, IS, IT, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MC, MD, MG, MK, ML, MN, MR, MW, MX, MZ, NA, NE, NG, NI, NL, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SI, SK, SL, SM, SN, SY, SZ, TD, TG, TJ, TM, TN, TR, TT, TZ, UA, UG, UZ, VC, VN, ZA, ZM, ZW only).
NOVARTIS PHARMA GmbH [AT/AT]; Brunner Strasse 59, A-1230 Vienna (AT) (AT only).
MANLEY, Paul, W. [GB/CH]; (CH) (For US Only).
SHIEH, Wen-Chung [US/US]; (US) (For US Only).
SUTTON, Paul, Allen [US/US]; (US) (For US Only).
KARPINSKI, Piotr, H. [US/US]; (US) (For US Only).
WU, Raeann [US/US]; (US) (For US Only).
MONNIER, Stéphanie [FR/FR]; (FR) (For US Only).
BROZIO, Jörg [DE/CH]; (CH) (For US Only)
Inventors: MANLEY, Paul, W.; (CH).
SHIEH, Wen-Chung; (US).
SUTTON, Paul, Allen; (US).
KARPINSKI, Piotr, H.; (US).
WU, Raeann; (US).
MONNIER, Stéphanie; (FR).
BROZIO, Jörg; (CH)
Agent: MC NALLY, Lydia, T.; Novartis, Corporate Intellectual Property, One Health Plaza, East Hanover, NJ 07936-1080 (US)
Priority Data:
60/701,405 20.07.2005 US
60/716,214 12.09.2005 US
Abstract: front page image
(EN)Crystalline forms of 4-methyl-N-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl]-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamide free base and salts thereof are prepared by various processes.
(FR)Selon l'invention, les formes cristallines de base libre 4-méthyl-N-[3-(4-méthyl-imidazol-1-yl)-5-trifluorométhyl-phényl]-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamide ainsi que les sels de ces dernières sont préparées au moyen de divers procédés.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)