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1. (WO2007014500) DIFFERENTIAL EXPRESSION GENE PROFILES AND APPLICATIONS IN MOLECULAR STAGING OF HUMAN GASTRIC CANCER
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2007/014500    International Application No.:    PCT/CN2005/001684
Publication Date: 08.02.2007 International Filing Date: 13.10.2005
IPC:
C12Q 1/68 (2006.01)
Applicants: CAPITALBIO CORPORATION [CN/CN]; 18 Life Science Parkway, Changping District, Beijing 102206 (CN) (For All Designated States Except US).
TSINGHUA UNIVERSITY [CN/CN]; Haidian District, Beijing 100084 (CN) (For All Designated States Except US).
BEIJING INSTITUTE FOR CANCER RESEARCH [CN/CN]; No.1, Dahongluochang Street, Xicheng District, Beijing_100034 (CN) (For All Designated States Except US).
LU, Youyong [CN/CN]; (CN) (For US Only).
GUO, Ruifang [CN/CN]; (CN) (For US Only).
ZANG, Shizhu [CN/CN]; (CN) (For US Only).
ZHANG, Liang [CN/CN]; (CN) (For US Only).
REN, Yonghong [CN/CN]; (CN) (For US Only).
ZHUANG, Yonglong [CN/CN]; (CN) (For US Only).
CHENG, Jing [CN/CN]; (CN) (For US Only)
Inventors: LU, Youyong; (CN).
GUO, Ruifang; (CN).
ZANG, Shizhu; (CN).
ZHANG, Liang; (CN).
REN, Yonghong; (CN).
ZHUANG, Yonglong; (CN).
CHENG, Jing; (CN)
Agent: JEEKAI & PARTNERS; Suite 602, Jinyu Tower, A129 West Xuan Wu Men Street, Xicheng District, Beijing 100031 (CN)
Priority Data:
200510088893.0 02.08.2005 CN
Title (EN) DIFFERENTIAL EXPRESSION GENE PROFILES AND APPLICATIONS IN MOLECULAR STAGING OF HUMAN GASTRIC CANCER
(FR) PROFILS DE GÈNES D’EXPRESSION DIFFÈRENTIELS ET APPLICATIONS DANS LA STADIFICATION MOLÉCULAIRE DU CANCER GASTRIQUE CHEZ L’HOMME
Abstract: front page image
(EN)The invention provides methods for detecting differential gene expression in intestinal gastric tissue in a mammal by comparing the expression of specific genes in an intestinal gastric tissue suspected of being cancerous with that of the corresponding adjacent intestinal gastric tissue or a normal gastric mucosa tissue. The methods can be used in diagnosing or monitoring the progression of intestinal gastric cancer and determining the levels of differentiation of intestinal gastric cancer. Systems and kits for methods of the invention are also provided.
(FR)La présente invention concerne des procédés destinés à détecter l’expression de gènes différentiels dans le tissu gastrique intestinal chez un mammifère en comparant l’expression de gènes spécifiques dans un tissu gastrique intestinal suspecté d’être cancéreux à celle du tissu gastrique intestinal adjacent correspondant ou d’un tissu de muqueuse gastrique normal. Les procédés peuvent être utilisés pour diagnostiquer ou contrôler la progression d’un cancer gastrique intestinal et pour déterminer les niveaux de différentiation du cancer gastrique intestinal. Des systèmes et des kits de l’invention sont également prévus.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)