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Machine translation
1. (WO2007014392) BENZOQUINONES OF ENHANCED BIOAVAILABILITY
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2007/014392    International Application No.:    PCT/US2006/029821
Publication Date: 01.02.2007 International Filing Date: 28.07.2006
IPC:
A61K 9/16 (2006.01), A61K 9/26 (2006.01), A61K 9/48 (2006.01), A61K 9/36 (2006.01), A61K 31/122 (2006.01), A61P 9/00 (2006.01)
Applicants: ISP INVESTMENTS INC. [US/US]; 300 DELAWARE AVENUE, Suite 303, Wilmington, DE 19801 (US) (For All Designated States Except US).
OLSEN, Stephen [US/US]; (US) (For US Only).
DONEY, John, Alfred [US/US]; (US) (For US Only).
SHORES, Christophen, Steven [US/US]; (US) (For US Only)
Inventors: OLSEN, Stephen; (US).
DONEY, John, Alfred; (US).
SHORES, Christophen, Steven; (US)
Agent: DAVIS, William, J.; INTERNATIONAL SPECIALTY PRODUCTS, LEGAL DEPARTMENT, BUILDING 8, 1361 Alps Road, Wayne, NJ 07470 (US)
Priority Data:
60/703,374 28.07.2005 US
60/756,454 05.01.2006 US
Title (EN) BENZOQUINONES OF ENHANCED BIOAVAILABILITY
(FR) BENZOQUINONES A BIODISPONIBILITE AMELIOREE
Abstract: front page image
(EN)Benzoquinone compositions of enhanced solubility and bioavailability are described that contain at least one benzoquinone with at least one solubility-enhancing polymer. In one embodiment, the benzoquinone is coenzyme Q10. Described methods to produce the bioenhanced products comprise dry blending and solvent spray drying. One aspect of the method includes the steps of providing a mixture comprising benzoquinone, a solubility-enhancing polymer and a solvent and removing the solvent to form amorphous benzoquinone. Products made by the invention's compositions and methods include pharmaceuticals, nutraceuticals, cosmetic, and personal care products for man and animal.
(FR)L'invention concerne des compositions de benzoquinone présentant une solubilité et une biodisponibilité améliorées, qui contiennent au moins un benzoquinone associé à au moins un polymère améliorant la solubilité. Dans un mode de réalisation, le benzoquinone est la co-enzyme Q10. L'invention concerne des méthodes de production de produits bioaméliorés mettant en oeuvre des processus de mélange à sec et de séchage par pulvérisation de solvant. Un aspect de la méthode consiste à utiliser un mélange comprenant benzoquinone, un polymère améliorant la solubilité et un solvant; elle consiste ensuite à éliminer le solvant pour former un benzoquinone amorphe. Des produits préparés avec les compositions et méthodes de l'invention comprennent des produits pharmaceutiques, des produits fonctionnels, des produits cosmétiques et des produits de soins personnels.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)