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1. (WO2007014391) TIGHT JUNCTION MODULATING PEPTIDE COMPONENTS FOR ENHANCING MUCOSAL DELIVERY OF THERAPEUTIC AGENTS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2007/014391    International Application No.:    PCT/US2006/029768
Publication Date: 01.02.2007 International Filing Date: 27.07.2006
IPC:
C07K 14/435 (2006.01), A61K 38/00 (2006.01)
Applicants: NASTECH PHARMACEUTICAL COMPANY INC. [US/US]; 3830 Monte Villa Parkway, Bothell, WA 98021-7266 (US) (For All Designated States Except US).
QUAY, Steven, C. [US/US]; (US) (For US Only).
QUAY, Shu-chih, Chen [US/US]; (US) (For US Only).
CUI, Kunyuan [US/US]; (US) (For US Only).
SILENO, Anthony, P. [US/US]; (US) (For US Only).
JOHNSON, Paul, Hickok [US/US]; (US) (For US Only).
HOUSTON, Michael, E. [CA/US]; (US) (For US Only).
COSTANTINO, Henry, R. [US/US]; (US) (For US Only).
TEMPLIN, Michael, V. [US/US]; (US) (For US Only).
LAMHARZI, Najib [US/US]; (US) (For US Only)
Inventors: QUAY, Steven, C.; (US).
QUAY, Shu-chih, Chen; (US).
CUI, Kunyuan; (US).
SILENO, Anthony, P.; (US).
JOHNSON, Paul, Hickok; (US).
HOUSTON, Michael, E.; (US).
COSTANTINO, Henry, R.; (US).
TEMPLIN, Michael, V.; (US).
LAMHARZI, Najib; (US)
Agent: KNUDSEN, Peter, J.; NASTECH PHARMACEUTICAL COMPANY INC., 3450 Monte Villa Park Way, Bothell, WA 98021-8906 (US)
Priority Data:
60/703,291 27.07.2005 US
60/703,289 27.07.2005 US
60/710,637 22.08.2005 US
60/750,886 16.12.2005 US
60/772,435 10.02.2006 US
Title (EN) TIGHT JUNCTION MODULATING PEPTIDE COMPONENTS FOR ENHANCING MUCOSAL DELIVERY OF THERAPEUTIC AGENTS
(FR) COMPOSANTES PEPTIDIQUES MODULANT LA JONCTION SERREE PERMETTANT D'AMELIORER LE DEGAGEMENT DES MUQUEUSES
Abstract: front page image
(EN)Compounds and components including sequences for mucosal epithelial transport of an active agent are given. Tight junction modulating peptide components are described for use in transport and delivery. Permeability can be enhanced with reversibility. Compounds and components for enhanced delivery may be peptide or protein variants, conjugates, or other analog types and structures.
(FR)L'invention concerne des composés et des composantes comprenant des séquences pour le transport épithélial muqueux d'un agent actif. Ces composantes peptidiques modulant la jonction serrée sont destinées à être utilisées dans le transport et le dégagement. La perméabilité peut être augmentée avec la réversibilité. L'invention concerne également des composés et composantes pour un dégagement amélioré, lesquels peuvent être des variants peptidiques ou protéiques, des conjugués, ou d'autres types et structures analogues.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)