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Machine translation
1. (WO2007014253) METHOD OF TREATING OR PREVENTING TISSUE DETERIORATION, INJURY OR DAMAGE DUE TO CONGESTIVE HEART FAILURE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2007/014253    International Application No.:    PCT/US2006/028996
Publication Date: 01.02.2007 International Filing Date: 26.07.2006
IPC:
A61K 38/00 (2006.01), A61K 38/04 (2006.01), C07K 5/00 (2006.01), C07K 7/00 (2006.01), C07K 16/00 (2006.01), C07K 17/00 (2006.01)
Applicants: REGENERX BIOPHARMACEUTICALS, INC. [US/US]; 3 Bethesda Metro Center, Suite 630, Bethesda, MD 20814 (US) (For All Designated States Except US).
CROCKFORD, David [US/US]; (US) (For US Only)
Inventors: CROCKFORD, David; (US)
Agent: REPPER, George R.; Rothwell, Figg, Ernst & Manbeck, 1425 K Street, NW, Suite 800, Washington, DC 20005 (US)
Priority Data:
60/702,269 26.07.2005 US
Title (EN) METHOD OF TREATING OR PREVENTING TISSUE DETERIORATION, INJURY OR DAMAGE DUE TO CONGESTIVE HEART FAILURE
(FR) METHODE PERMETTANT DE TRAITER OU DE PREVENIR LA DETERIORATION, LES LESIONS OU LES DOMMAGES TISSULAIRES CAUSES PAR L'INSUFFISANCE CARDIAQUE CONGESTIVE
Abstract: front page image
(EN)A method of treatment for treating, preventing, inhibiting or reducing tissue deterioration, injury or damage due to congestive heart failure disease, or for restoring tissue adversely affected by said disease, in a subject, includes administering to a subject an effective amount of a composition including a peptide agent including amino acid sequence LKKTET or LKKTNT, a conservative variant thereof, or a peptide agent that stimulates production of an LKKTET or LKKTNT peptide, or a conservative variant thereof, in the tissue.
(FR)La présente invention se rapporte à une méthode permettant de traiter, de prévenir, d'inhiber ou de réduire la détérioration, les lésions ou les dommages tissulaires causés par l'insuffisance cardiaque congestive, ou de restaurer un tissu atteint par ladite maladie, chez un sujet. La méthode selon l'invention consiste à administrer à un sujet, dans un tel tissu, une dose efficace d'une composition contenant un agent peptidique renfermant une séquence d'acides aminés LKKTET ou LKKTNT, une variante conservatrice d'un tel agent, ou un agent peptidique qui stimule la production d'un peptide LKKTET ou LKKTNT, ou une variante conservatrice d'un tel agent.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)