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1. (WO2007013480) SCREENING AND THERAPEUTIC METHOD FOR NSCLC TARGETING CDCA1-KNTC2 COMPLEX
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2007/013480    International Application No.:    PCT/JP2006/314715
Publication Date: 01.02.2007 International Filing Date: 19.07.2006
IPC:
G01N 33/574 (2006.01), A61P 35/00 (2006.01), A61K 47/46 (2006.01), A61K 31/70 (2006.01)
Applicants: ONCOTHERAPY SCIENCE, INC. [JP/JP]; 2-1, Sakado 3-chome, Takatsu-ku, Kawasaki-shi, Kanagawa, 2130012 (JP) (For All Designated States Except US).
NAKAMURA, Yusuke [JP/JP]; (JP) (For US Only).
DAIGO, Yataro [JP/JP]; (JP) (For US Only).
NAKATSURU, Shuichi [JP/JP]; (JP) (For US Only)
Inventors: NAKAMURA, Yusuke; (JP).
DAIGO, Yataro; (JP).
NAKATSURU, Shuichi; (JP)
Agent: SHIMIZU, Hatsushi; Kantetsu Tsukuba Bldg. 6F, 1-1-1, Oroshi-machi, Tsuchiura-shi, Ibaraki 3000847 (JP)
Priority Data:
60/703,704 29.07.2005 US
Title (EN) SCREENING AND THERAPEUTIC METHOD FOR NSCLC TARGETING CDCA1-KNTC2 COMPLEX
(FR) CRIBLAGE ET METHODE THERAPEUTIQUE ANTI-NSCLC CIBLANT LE COMPLEXE CDA1-KNTC2
Abstract: front page image
(EN)The present invention is based on the observation that the co-activation of CDCA1 and KNTC2, and their cognate interactions, play significant roles in lung-cancer progression and that methods of inhibiting the complex can be used to treat non-small-cell lung cancer.
(FR)L'invention repose sur l'observation selon laquelle la co-activation de CDCA1 et de KNTC2, et de leurs interactions connexes, joue un rôle important dans l'évolution du cancer du poumon; ainsi que sur des procédés d'inhibition de ce complexe qui peuvent servir à traiter le cancer du poumon non à petites cellules.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)