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Machine translation
1. (WO2007012964) PREPARATION OF ALKYLPIPERAZINYLPHENYL COMPOUNDS BY CLASSICAL RESOLUTION
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2007/012964    International Application No.:    PCT/IB2006/002115
Publication Date: 01.02.2007 International Filing Date: 20.07.2006
IPC:
C07D 211/76 (2006.01), C07D 265/32 (2006.01)
Applicants: PFIZER PRODUCTS INC. [US/US]; Eastern Point Road, Groton, CT 06340 (US) (For All Designated States Except US).
CARON, Stephane [CA/US]; (US) (For US Only).
MY DO, Nga [US/US]; (US) (For US Only).
MCDERMOTT, Ruth, Elsbree [US/US]; (US) (For US Only)
Inventors: CARON, Stephane; (US).
MY DO, Nga; (US).
MCDERMOTT, Ruth, Elsbree; (US)
Agent: FULLER, Grover, F., Jr.; Pfizer Inc., 150 East 42nd Street, New York, NY 10017-5612 (US)
Priority Data:
60/702,219 25.07.2005 US
Title (EN) PREPARATION OF ALKYLPIPERAZINYLPHENYL COMPOUNDS BY CLASSICAL RESOLUTION
(FR) PRÉPARATION DE COMPOSÉS D'ALKYLPIPÉRAZINYLPHÉNYLE PAR DÉDOUBLEMENT CLASSIQUE
Abstract: front page image
(EN)The present invention relates to a novel method for the optical resolution of racemic alkylpiperazinylphenyl compounds that include selective 5HTiD antagonists useful in treating or preventing depression, anxiety, migraine, obsessive compulsive disorder (OCD) and other disorders for which a 5-HT1 agonist or antagonist is indicated having the formula (I), wherein X, R1, and R2 have the definitions provided herein.
(FR)La présente invention concerne un procédé innovant de dédoublement optique de composés racémiques d'alkylpipérazinylphényle. Ces composés incluent des antagonistes sélectifs de 5HTiD utiles pour le traitement ou la prévention de la dépression, de l 'anxiété, de la migraine, du trouble obsessionnel impulsif (Obsessive-Compulsive Disorder ; OCD) et d'autres troubles pour lesquels est indiqué un agoniste ou un antagoniste de 5-HT1 de formule (I), dans laquelle X, R1 et R2 sont conformes aux définitions fournies ici.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)