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1. (WO2007011904) RECOMBINANT FLU VACCINES
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2007/011904 International Application No.: PCT/US2006/027764
Publication Date: 25.01.2007 International Filing Date: 19.07.2006
IPC:
A61K 39/145 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
12
Viral antigens
145
Orthomyxoviridae, e.g. influenza virus
Applicants:
DOW GLOBAL TECHNOLOGIES INC. [US/US]; Washington Street 1790 Building Midland, MI 48674, US (AllExceptUS)
RASOCHOVA, Lada [US/US]; US (UsOnly)
RADAM, Jason, M. [US/US]; US (UsOnly)
PHELPS, Jamie, P. [US/US]; US (UsOnly)
DANG, Nghiep [US/US]; US (UsOnly)
Inventors:
RASOCHOVA, Lada; US
RADAM, Jason, M.; US
PHELPS, Jamie, P.; US
DANG, Nghiep; US
Agent:
BELLOWS, Brent, R.; KING & SPALDING LLP 1180 Peachtree Street, NE 34th Floor Atlanta, GA 30309-3521, US
Priority Data:
60/700,60119.07.2005US
Title (EN) RECOMBINANT FLU VACCINES
(FR) VACCINS RECOMBINANTS CONTRE LA GRIPPE
Abstract:
(EN) The present invention provides compositions for use as vaccines against the influenza virus, and rapid methods of producing such compositions. The composition include i) at least one peptide derived from an influenza virus, wherein the peptide is fused to a capsid protein derived from a plant virus forming a recombinant capsid fusion peptide and ii) at least one isolated antigenic protein or protein fragment derived from a human or avian influenza virus. The isolated antigenic protein or protein fragment derived from the human or avian influenza virus can be conjugated to the surface of the recombinant capsid fusion peptide.
(FR) La présente invention concerne des compositions à utiliser comme vaccins contre le virus grippal, et des procédés rapides de production de telles compositions. Cette composition contient i) au moins un peptide dérivé du virus grippal, ce peptide étant fixé à une protéine de capside dérivée d'un virus de plante formant un peptide de fusion de capside recombinant et ii) au moins une protéine antigénique isolée ou un fragment protéique dérivé(e) d'un virus de grippe humaine ou aviaire. La protéine antigénique isolée ou le fragment protéique dérivé(e) du virus de la grippe humaine ou aviaire peut être conjugué à la surface du peptide de fusion de capside recombinant.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
MXMX/a/2008/000890KR1020080028941EP1909829BRPI0613625-7JP2009502789CN101227920
CA2615658AU2006270065IN271/DELNP/2008