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1. (WO2007011880) ENHANCED OCULAR NEUROPROTECTION/NEUROSTIMULATION
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2007/011880    International Application No.:    PCT/US2006/027713
Publication Date: 25.01.2007 International Filing Date: 18.07.2006
Chapter 2 Demand Filed:    09.08.2007    
IPC:
A61K 31/365 (2006.01), A61K 31/436 (2006.01), A61K 31/192 (2006.01), A61K 31/56 (2006.01), A61K 31/60 (2006.01), A61K 31/7048 (2006.01), A61K 38/13 (2006.01), A61K 38/18 (2006.01), A61K 38/19 (2006.01), A61P 27/02 (2006.01), A61P 27/06 (2006.01), A61K 45/06 (2006.01)
Applicants: MINU, L.L.C. [US/US]; 321 Miles Branch Road, Pittsboro, NC 27312 (US) (For All Designated States Except US).
PEYMAN, Gholam, A. [US/US]; (US) (For US Only)
Inventors: PEYMAN, Gholam, A.; (US)
Agent: LYMAN, Beverly, A.; Wood, Herron & Evans, L.L.P., 441 Vine Street, 2700 Carew Tower, Cincinnati, OH 45202 (US).
ARENDS, WILLIAM GERRIT; LLOYD WISE, COMMONWEALTH HOUSE, 1-19 NEW OXFORD STREET, LONDON WC1 A 1 LW (GB)
Priority Data:
11/183,355 18.07.2005 US
11/263,737 01.11.2005 US
Title (EN) ENHANCED OCULAR NEUROPROTECTION/NEUROSTIMULATION
(FR) NEURO-PROTECTION/NEURO-STIMULATION OCULAIRE AMELIOREE
Abstract: front page image
(EN)An ocular method comprising non-systemic localized ocular administration of a pharmaceutically acceptable formulation and effective concentration of at least one neuro-stimulatory and/or neuro-protective macrolide or other agent for a duration sufficient to enhance viability, confer protection, and/or reduce degeneration of retinal neural cells; enhance corneal sensation and/or ameliorate, and/or prevent ocular scarring. The method is used in a patient having or at risk for developing glaucoma, retinitis pigmentosa, or another ocular neuro-associated disease.
(FR)L'invention concerne un procédé oculaire comprenant une administration oculaire localisée non-systémique d'une formulation pharmaceutiquement acceptable, et à une concentration efficace, d'au moins un macrolide neuro-stimulateur et/ou neuro-protecteur ou autre agent, pendant une durée suffisante pour améliorer la viabilité, conférer la protection et/ou réduire la dégénérescence des cellules neurales rétiniennes ; améliorer la sensation cornéenne et/ou améliorer et/ou prévenir une cicatrisation oculaire. Le procédé est utilisé chez un patient présentant un glaucome, ou risquant de développer un glaucome, une rétinite pigmentaire ou autre maladie oculaire neuro-associée.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)