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Machine translation
1. (WO2007011820) ARYL-AND HETEROARYL-SUBSTITUTED TETRAHYDROBENZAZEPINES AND USE THEREOF TO BLOCK REUPTAKE OF NOREPINEPHRINE, DOPAMINE, AND SEROTONIN
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2007/011820    International Application No.:    PCT/US2006/027574
Publication Date: 25.01.2007 International Filing Date: 17.07.2006
IPC:
A61P 25/00 (2006.01), A61K 31/55 (2006.01), C07D 223/16 (2006.01)
Applicants: AMR TECHNOLOGY, INC. [US/US]; 5429 Main Street, P.O. Box 2587, Manchester Center, VT 05255-2587 (US) (For All Designated States Except US).
BRISTOL-MYERS SQUIBB COMPANY [US/US]; Lawrenceville-Princeton Road, Princeton, VT 05255-2587 (US) (For All Designated States Except US)
Inventors: MOLINO, Bruce, F.; (US).
LIU, Shuang; (US).
SAMBANDAM, Aruna; (US).
GUZZO, Peter, R.; (US).
HU, Min; (US).
ZHA, Congxiang; (US).
NACRO, Kassoum; (US).
MANNING, David, D.; (US).
ISHERWOOD, Matthew, L.; (US).
FLEMING, Kristen, N.; (US).
CUI, Wenge; (US).
OLSON, Richard, E.; (US)
Agent: CHOI, Alice, Y.; Nixon Peabody LLP, Clinton Square, P.O. Box 31051, Rochester, NY 14603-1051 (US)
Priority Data:
60/700,057 15.07.2005 US
Title (EN) ARYL-AND HETEROARYL-SUBSTITUTED TETRAHYDROBENZAZEPINES AND USE THEREOF TO BLOCK REUPTAKE OF NOREPINEPHRINE, DOPAMINE, AND SEROTONIN
(FR) TETRAHYDROBENZAZEPINES SUBSTITUEES PAR ARYLE ET HETEROARYLE, ET LEUR UTILISATION POUR BLOQUER LA REABSORPTION DE LA NORADRENALINE, DE LA DOPAMINE, ET DE LA SEROTONINE
Abstract: front page image
(EN)The compounds of the present invention are represented by the following aryl- and heteroaryl-substituted tetrahydrobenzazepine and dihydrobenzazapine derivatives having formulae I(A-E) and formula (II) where the carbon atom designated * is in the R or S configuration, and the substituents X and R1-R9 are as defined herein.
(FR)Les composés de l'invention sont représentés par la tétrahydrobenzazépine substituée par aryle et hétéroaryle et par des dérivés de dihydrobenzazapine de formules (I)(A-E) et de formule (II), dans lesquelles l'atome de carbone désigné* se trouve dans la configuration R ou S, et les substituants X et R1-R9 sont tels que définis dans le mémorandum descriptif.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)