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1. (WO2007011708) STENT WITH POLYMER COATING CONTAINING AMORPHOUS RAPAMYCIN
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2007/011708 International Application No.: PCT/US2006/027322
Publication Date: 25.01.2007 International Filing Date: 14.07.2006
IPC:
A61F 2/06 (2006.01) ,A61L 27/00 (2006.01) ,B05D 7/22 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
F
FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
2
Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
02
Prostheses implantable into the body
04
Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
06
Blood vessels
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
L
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
27
Materials for prostheses or for coating prostheses
B PERFORMING OPERATIONS; TRANSPORTING
05
SPRAYING OR ATOMISING IN GENERAL; APPLYING LIQUIDS OR OTHER FLUENT MATERIALS TO SURFACES, IN GENERAL
D
PROCESSES FOR APPLYING LIQUIDS OR OTHER FLUENT MATERIALS TO SURFACES, IN GENERAL
7
Processes, other than flocking, specially adapted for applying liquids or other fluent materials to particular surfaces or for applying particular liquids or other fluent materials
22
to internal surfaces, e.g. of tubes
Applicants:
MICELL TECHNOLOGIES, INC. [US/US]; 7516 Precision Drive Raleigh, NC 27617, US (AllExceptUS)
TAYLOR, Doug [US/US]; US (UsOnly)
DAYOUNG, James [US/US]; US (UsOnly)
MCCLAIN, Jim [US/US]; US (UsOnly)
Inventors:
TAYLOR, Doug; US
DAYOUNG, James; US
MCCLAIN, Jim; US
Agent:
ELAMRANI, Samir ; WILSON SONSINI GOODRICH & ROSATI 650 Page Mill Road Palo Alto, CA 94304-1050, US
Priority Data:
60/699,65015.07.2005US
60/765,33903.02.2006US
Title (EN) STENT WITH POLYMER COATING CONTAINING AMORPHOUS RAPAMYCIN
(FR) STENT A REVETEMENT POLYMERE RENFERMANT DE LA RAPAMYCINE AMORPHE
Abstract:
(EN) A coated coronary stent, comprising: a stainless steel sent framework coated with a primer layer of Parylene C; and a rapamycin-polyrner coating having substantially uniform thickness disposed on the stent framework, wherein the rapamycin-polymer coating comprises polybutyl methacrylate (PBMA), polyethylene-co-vinyl acetate (PEVA) and rapamycin, wherein substantially all of the rapamycin in the coating is in amorphous form and substantially uniformly dispersed within the rapamycin-polymer coating.
(FR) L'invention concerne un stent coronaire revêtu comprenant: un cadre en acier inoxydable revêtu d'une couche d'amorce de Parylène C; et un revêtement de rapamycine-polymère présentant une épaisseur sensiblement uniforme et déposé sur le cadre du stent, le revêtement rapamycine-polymère comprenant du polybutyl méthacrylate (PBMA), du polyéthylène-co-vinyl acétate (PEVA) et de la rapamycine, sensiblement l'ensemble de la rapamycine dans le revêtement étant sous forme amorphe et sensiblement dispersé de manière uniforme dans le revêtement rapamycine-polymère.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
US20090062909