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1. (WO2007011699) USE OF NON-ANTIBACTERIAL TETRACYCLINE FORMULATIONS FOR INHIBITING BACTERIAL SPORES
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2007/011699 International Application No.: PCT/US2006/027313
Publication Date: 25.01.2007 International Filing Date: 14.07.2006
IPC:
A61K 31/65 (2006.01) ,A61P 31/04 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
65
Tetracyclines
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31
Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
04
Antibacterial agents
Applicants:
RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK [US/US]; Post Office Box 9 Albany, NY 12201-0009, US (AllExceptUS)
WALKER, Stephen, G. [CA/US]; US (UsOnly)
GOLUB, Lorne, M. [US/US]; US (UsOnly)
SIMON, Sanford, R. [US/US]; US (UsOnly)
Inventors:
WALKER, Stephen, G.; US
GOLUB, Lorne, M.; US
SIMON, Sanford, R.; US
Agent:
BARON, Ronald, J. ; HOFFMANN & BARON, LLP 6900 Jericho Turnpike Syosset, NY 11791, US
Priority Data:
11/182,50015.07.2005US
11/317,63523.12.2005US
Title (EN) USE OF NON-ANTIBACTERIAL TETRACYCLINE FORMULATIONS FOR INHIBITING BACTERIAL SPORES
(FR) UTILISATION DE FORMULATIONS DE TETRACYCLINE NON ANTIBACTERIENNE POUR INHIBER LES SPORES BACTERIENNES
Abstract:
(EN) The invention relates to a method for inhibiting bacterial spores from becoming infectious vegetative cells in a mammal in need thereof. In another embodiment, invention relates to a method for inhibiting outgrowth of bacterial spores in a mammal in need thereof. The method comprises administering to the mammal an effective amount of a non-antibacterial tetracycline formulation. In one embodiment, the non-antibacterial tetracycline formulation comprises an antibacterial tetracycline in a sub-antibacterial amount. In another embodiment, the non-antibacterial tetracycline formulation comprises a non-antibacterial tetracycline.
(FR) L'invention concerne un procédé permettant d'inhiber les spores bactériennes pour les empêcher de devenir des cellules végétatives infectieuses chez un mammifère en ayant besoin. Dans un autre mode de réalisation, l'invention concerne un procédé d'inhibition de l'excroissance de spores bactériennes chez un mammifère en ayant besoin. Ce procédé consiste à administrer au mammifère une quantité efficace d'une formulation de tétracycline non bactérienne. Dans un mode de réalisation, la formulation de tétracycline non bactérienne contient une tétracycline antibactérienne dans une quantité sub-antibactérienne. Dans un autre mode de réalisation, la formulation tétracycline non bactérienne contient une tétracycline non bactérienne.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
NZ565113KR1020080034434EP1906970JP2009501718US20070015739CN101460177
AU2006270213