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1. (WO2007011698) HUMANIZED ANTIBODY CONJUGATES AND RELATED METHODS, ASSAYS, REAGENTS, AND KITS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2007/011698 International Application No.: PCT/US2006/027312
Publication Date: 25.01.2007 International Filing Date: 14.07.2006
IPC:
C12P 21/08 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
P
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
21
Preparation of peptides or proteins
08
Monoclonal antibodies
Applicants:
SIEMENS MEDICAL SOLUTIONS DIAGNOSTICS [US/US]; LAW & PATENTS DEPT. 511 Benedict Avenue Tarrytown, NY 10591, US (AllExceptUS)
ANDERSON-MAUSER, Linda-Marie [US/US]; US (UsOnly)
FOLTZ, Mary, Margaret [US/US]; US (UsOnly)
DWYER, Robert, John [CA/US]; US (UsOnly)
Inventors:
ANDERSON-MAUSER, Linda-Marie; US
FOLTZ, Mary, Margaret; US
DWYER, Robert, John; US
Agent:
KLAWITTER, Andrew, L.; Siemens Corporation Intellectual Property Dept. 170 Wood Avenue South Iselin, NJ 08830, US
Priority Data:
60/699,61815.07.2005US
60/708,36131.08.2005US
Title (EN) HUMANIZED ANTIBODY CONJUGATES AND RELATED METHODS, ASSAYS, REAGENTS, AND KITS
(FR) CONJUGUES D'ANTICORPS HUMANISES ET PROCEDES CORRESPONDANTS, ESSAIS BIOLOGIQUES, REACTIFS ET TROUSSES
Abstract:
(EN) The invention provides synthetically and recombinantly-derived humanized antibody conjugates and related methods, diagnostic assays, reagents, and kits. In one embodiment, the invention provides humanized antibody conjugates comprising a human immunoglobulin fragment which is bound by a cross-linking functional group to a non-human antibody fragment (e.g., a non-human monoclonal antibody fragment) comprising an antigen-binding amino acid sequence.
(FR) L'invention concerne des conjugués d'anticorps dérivés synthétiquement et par voie recombinante et les procédés correspondants, de dosages diagnostics, réactifs et trousses. Dans un mode de réalisation, l'invention concerne des conjugués d'anticorps humanisés contenant un fragment d'immunoglobuline humain qui est lié par un groupe fonctionnel de réticulation à un fragment d'anticorps non-humain (par ex., un fragment d'anticorps monoclonal non-humain) contenant une séquence d'acide aminé à liaison d'antigène.
front page image
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP1922412