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1. (WO2007011622) MICROFLUIDIC METHODS AND APPARATUSES FOR SAMPLE PREPARATION AND ANALYSIS
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2007/011622 International Application No.: PCT/US2006/027111
Publication Date: 25.01.2007 International Filing Date: 13.07.2006
IPC:
C12Q 1/68 (2006.01) ,G01N 15/06 (2006.01) ,G01N 35/00 (2006.01) ,G01N 33/00 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Q
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1
Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions
68
involving nucleic acids
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
15
Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
06
Investigating concentration of particle suspensions
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
35
Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/-G01N33/148; Handling materials therefor
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
Applicants:
YANTZ, Gregory, R. [US/US]; US (UsOnly)
LARSON, Jonathan, W. [US/US]; US (UsOnly)
GILMANSHIN, Rudolf [RU/US]; US (UsOnly)
U.S. GENOMICS, INC. [US/US]; 12 Gill Street Woburn, MA 01801, US (AllExceptUS)
Inventors:
YANTZ, Gregory, R.; US
LARSON, Jonathan, W.; US
GILMANSHIN, Rudolf; US
Agent:
NORFLEET, Walt; WOLF, GREENFIELD & SACKS, P.C. 600 Atlantic Avenue Boston, MA 02210, US
Priority Data:
60/700,48018.07.2005US
60/700,49018.07.2005US
60/700,68918.07.2005US
Title (EN) MICROFLUIDIC METHODS AND APPARATUSES FOR SAMPLE PREPARATION AND ANALYSIS
(FR) PROCEDES MICROFLUIDIQUES ET DISPOSITIFS DE PREPARATION ET D'ANALYSE D'ECHANTILLONS
Abstract:
(EN) Microfludic channels are constructed for use in preparing and/or analyzing samples. In one embodiment, a microfluidic channel receives a carrier fluid having both non-targets and targets. The non-targets are moved from the carrier fluid by diffusion and into sheathing fluids also present in the channel before contents of the carrier fluid are analyzed. In another embodiment, a microchannel delivers multiple fluid samples from an upstream portion to a downstream portion of the channel where each of the fluid samples are separated from one another by a sheathing fluid that also travels toward the downstream portion. In another embodiment, a microchannel is constructed to create multiple elongational flows in series that can align polymers from a coiled state.
(FR) Selon l'invention, des canaux microfluidiques sont produits pour être utilisés pour la préparation et/ou l'analyse d'échantillons. Dans un mode de réalisation, un canal microfluidique reçoit un liquide de support comprenant à la fois des cibles et des non cibles. Les non cibles sont mises en mouvement depuis le liquide de support par diffusion et dans des liquides de gainage également présents dans le canal avant analyse des contenus du liquide de support. Dans un autre mode de réalisation, un microcanal fournit de multiples échantillons de liquide d'une partie amont à une partie aval du canal, chacun des échantillons de liquide étant séparé des autres par un liquide de gainage qui circule également en direction de la partie aval. Dans un autre mode de réalisation, un microcanal est produit pour créer de multiples flux allongés en séries qui peuvent aligner des polymères à partir d'un état hélicoïdal.
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Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)