Search International and National Patent Collections
Some content of this application is unavailable at the moment.
If this situation persists, please contact us atFeedback&Contact
1. (WO2007011619) HIGHLY BIOAVAILABLE ORAL DELAYED RELEASE DOSAGE FORMS OF O-DESMETHYLVENLAFAXINE SUCCINATE
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2007/011619 International Application No.: PCT/US2006/027106
Publication Date: 25.01.2007 International Filing Date: 13.07.2006
IPC:
A61K 9/32 (2006.01) ,A61K 9/50 (2006.01) ,A61K 31/135 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
20
Pills, lozenges or tablets
28
Dragees; Coated pills or tablets
30
Organic coatings
32
containing solid synthetic polymers
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
48
Preparations in capsules, e.g. of gelatin, of chocolate
50
Microcapsules
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
13
Amines, e.g. amantadine
135
having aromatic rings, e.g. methadone
Applicants:
WYETH [US/US]; Five Giralda Farms Madison, NJ 07940, US (AllExceptUS)
SHAH, Syed, M. [US/US]; US (UsOnly)
FAWZI, Mahdi, B. [US/US]; US (UsOnly)
DIORIO, Christopher, Richard [US/US]; US (UsOnly)
Inventors:
SHAH, Syed, M.; US
FAWZI, Mahdi, B.; US
DIORIO, Christopher, Richard; US
Agent:
KODROFF, Cathy, A.; Howson And Howson 501 Office Center Drive Suite 210 Fort Washington, PA 19034 , US
Priority Data:
60/699,62315.07.2005US
Title (EN) HIGHLY BIOAVAILABLE ORAL DELAYED RELEASE DOSAGE FORMS OF O-DESMETHYLVENLAFAXINE SUCCINATE
(FR) FORMES PHARMACEUTIQUES ORALES HAUTEMENT BIODISPONIBLES A LIBERATION RETARDEE, DE O-DESMETHYLVENLAFAXINE SUCCINATE
Abstract:
(EN) An oral, highly bioavailable unit dosage form of O-desmethylvenlafaxine succinate (DVS) having a delayed release of at least about one hour and a sustained release over multiple hours to provide a total release of greater than about 85 % within about 12 to about 14 hours is described. In one embodiment, the superbioavailable DVS composition has a delayed release of about two hours and a total release of greater than about 95 % within about 12 to about 14 hours. Use of the formulation in treating depression and reducing the gastrointestinal side-effects of O-desmethylvenlafaxine (ODV) is also described.
(FR) Formes pharmaceutiques orales hautement biodisponibles à libération retardée, de O-desméthylvenlafaxine succinate (DVS), à libération retardée d'au moins une heure et libération prolongée de plusieurs heures donnant une libération totale supérieure à environ 85 % dans une fourchette d'environ 12 à environ 14 heures. Selon une variante, la composition DVS ultrabiodisponible a une libération retardée d'environ deux heures et une libération totale supérieure à environ 95 % dans une fourchette d'environ 12 à environ 14 heures. Egalement, utilisation de ce type de formulation pour le traitement de la dépression et la réduction des effets secondaires gastro-intestinaux du produit O-desméthylvenlafaxine (ODV).
front page image
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
NO20080088NZ565082MXMX/a/2008/000666IL188313AR054833VN17480
PE2007-0192EP1904040JP2009501233CN101247791CA2612960AU2006270315
BRPI0613484ID048.2044MYPI 20063343TH88087IN185/KOLNP/2008