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Machine translation
1. (WO2007011610) PROTEIN FORMULATION FOR PROMOTING HARD TISSUE FORMATION
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2007/011610    International Application No.:    PCT/US2006/027075
Publication Date: 25.01.2007 International Filing Date: 12.07.2006
IPC:
A61K 38/00 (2006.01), A61K 38/02 (2006.01), A61K 38/03 (2006.01), A61K 38/04 (2006.01), A61K 38/08 (2006.01), A61K 38/10 (2006.01), A61K 38/16 (2006.01), A61K 38/18 (2006.01)
Applicants: ACOLOGIX, INC. [US/US]; 3960 Point Eden Way, Hayward, CA 94545 (US) (For All Designated States Except US).
LAZAROV, Mirella [BG/US]; (US) (For US Only).
MIDDLETON-HARDIE, Catherine [NZ/US]; (US) (For US Only).
ROSEN, David [US/US]; (US) (For US Only)
Inventors: LAZAROV, Mirella; (US).
MIDDLETON-HARDIE, Catherine; (US).
ROSEN, David; (US)
Agent: BOZICEVIC, Karl; BOZICEVIC, FIELD & FRANCIS LLP, 1900 University Avenue, Suite 200, East Palo Alto, CA 94303 (US)
Priority Data:
60/700,518 18.07.2005 US
60/747,143 12.05.2006 US
60/747,255 15.05.2006 US
60/803,327 26.05.2006 US
60/805,201 19.06.2006 US
Title (EN) PROTEIN FORMULATION FOR PROMOTING HARD TISSUE FORMATION
(FR) FORMULATION DE PROTEINES PERMETTANT DE FAVORISER LA FORMATION DE TISSUS DURS
Abstract: front page image
(EN)Formulations and kits used to promote biological processes to form or regenerate new hard tissues such as bones, cartilage, and/or dental tissues are disclosed. The formulation comprises a carrier and two or more proteins and enhances biological activities of a hard tissue growth and differentiation factor characterized by specific and selective upregulation and/or extension of the retention time of the intracellular enzymes and signaling molecules that play important roles to proliferate, differentiate, maturate, and/or mineralize the hard tissue forming cells.
(FR)L'invention concerne des formulations et des kits servant à favoriser des processus biologiques pour la formation ou la régénération de nouveaux tissus durs de type os, cartilages, et/ou tissus dentaires. La formulation de l'invention comprend un excipient et au moins deux protéines et augmente les activités biologiques d'un facteur de croissance et de différenciation de tissus durs caractérisé par la régulation à la hausse et/ou l'extension spécifiques et sélectives du temps de rétention des enzymes intracellulaires et des molécules de signalisation qui jouent des rôles importants pour la prolifération, la différenciation, la maturation, et/ou la minéralisation des cellules formant des tissus durs.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)