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1. (WO2007011595) NEURAL REGENERATION PEPTIDES AND ANTIOXIDANTS PROTECT NEURONS FROM DEGENERATION
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2007/011595 International Application No.: PCT/US2006/026994
Publication Date: 25.01.2007 International Filing Date: 13.07.2006
IPC:
C12Q 1/68 (2006.01) ,A61K 38/17 (2006.01) ,C07H 21/04 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Q
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1
Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions
68
involving nucleic acids
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
16
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17
from animals; from humans
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
H
SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
21
Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
04
with deoxyribosyl as saccharide radical
Applicants:
NEUREN PHARMACEUTICALS LIMITED [NZ/NZ]; Level 3, 2-6 Park Avenue Grafton, Auckland, NZ (AllExceptUS)
NEUREN PHARMACEUTICALS INC. [US/US]; 3 Bethesda Metro Center, Suite 700 Bethesda, Maryland 20814-5337, US (MG)
SIEG, Frank [DE/NZ]; NZ (UsOnly)
Inventors:
SIEG, Frank; NZ
Agent:
BORSON, Benjamin, D. Jr., ; Fliesler Meyer LLP Four Embarcadero Center, Fourth Floor San Francisco, California 94111-4156, US
Priority Data:
60/699,64215.07.2005US
60/714,91607.09.2005US
Title (EN) NEURAL REGENERATION PEPTIDES AND ANTIOXIDANTS PROTECT NEURONS FROM DEGENERATION
(FR) PEPTIDES DE REGENERATION NEURALE ET ANTIOXYDANTS PROTEGEANT LES NEURONES DE LA DEGENERESCENCE
Abstract:
(EN) Aspects of this invention include compositions for treating conditions in which neurons would otherwise degenerate or die as a result of an insult to the nervous system. Other aspects include methods for treating conditions in which neurons would otherwise degenerate or die as a result of an insult to the nervous system. Compositions include a neural regeneration peptide (NRP) and an antioxidant. The methods include administering to a subject in need thereof, a composition comprising a neural regeneration peptide and an antioxidant. Compositions including one or more NRPs and one or more antioxidants can also be used in vitro, to promote growth and differentiation of neural cell cultures. Kits include one or more NRPs, one or more antioxidants, solvents for preparing solutions, a mixing vial and instructions for use.
(FR) L'invention porte par certains aspects sur des compositions de traitement d'états de dégénérescence ou de mort des neurones dus à des atteintes au système nerveux. D'autres aspects de l'invention ont trait à des méthodes de traitement de tels états. Lesdites compositions comportent un peptide de régénération neurale (NRP) et un antioxydant. Une telle méthode consiste à administrer à un sujet le nécessitant une telle composition. L'invention porte également: sur des compositions comprenant un ou des NRPs et un ou des antioxydants, et pouvant s'utiliser également in vitro pour promouvoir la croissance et la différenciation de cultures de cellules neurales; et sur des trousses comprenant un ou des NRPs et un ou des antioxydants, des solvant de préparation de solutions et un flacon mélangeur et son mode d'emploi.
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Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)