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1. (WO2007011594) HIGHLY SELECTIVE SEROTONIN AND NOREPINEPHRINE DUAL REUPTAKE INHIBITOR AND USE THEREOF
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2007/011594 International Application No.: PCT/US2006/026991
Publication Date: 25.01.2007 International Filing Date: 13.07.2006
IPC:
C07C 215/64 (2006.01) ,A61K 31/135 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
C
ACYCLIC OR CARBOCYCLIC COMPOUNDS
215
Compounds containing amino and hydroxy groups bound to the same carbon skeleton
46
having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
64
with rings other than six-membered aromatic rings being part of the carbon skeleton
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
13
Amines, e.g. amantadine
135
having aromatic rings, e.g. methadone
Applicants:
WYETH [US/US]; Five Giralda Farms Madison, NJ 07940, US (AllExceptUS)
SHAH, Syed, M. [US/US]; US (UsOnly)
EHRNSPERGER, Eric, C. [US/US]; US (UsOnly)
SAUNDERS, Richard, W. [GB/US]; US (UsOnly)
FAWZI, Mahdi, B. [US/US]; US (UsOnly)
GALANTE, Rocco, J. [US/US]; US (UsOnly)
WHITESIDE, Garth, T. [GB/US]; US (UsOnly)
Inventors:
SHAH, Syed, M.; US
EHRNSPERGER, Eric, C.; US
SAUNDERS, Richard, W.; US
FAWZI, Mahdi, B.; US
GALANTE, Rocco, J.; US
WHITESIDE, Garth, T.; US
Agent:
BARNHARD, Elizabeth, M. ; Wyeth Patent Law Department Five Giralda Farms Madison, New Jersey 07940, US
Priority Data:
60/699,66515.07.2005US
Title (EN) HIGHLY SELECTIVE SEROTONIN AND NOREPINEPHRINE DUAL REUPTAKE INHIBITOR AND USE THEREOF
(FR) INHIBITEUR DOUBLE HAUTEMENT SELECTIF DE RECAPTAGE DE LA SEROTONINE ET DE LA NORADRENALINE ET SON UTILISATION
Abstract:
(EN) Highly selective dual serotonin and norepinephrine reuptake inhibitors are provided. These compounds have a lower side-effect profile and are useful in compositions and products for use in treatment of a variety of conditions including depression, fibromyalgia, anxiety, panic disorder, agoraphobia, post traumatic stress disorder, premenstrual dysphoric disorder, attention deficit disorder, obsessive compulsive disorder, social anxiety disorder, generalized anxiety disorder, autism, schizophrenia, obesity, anorexia nervosa, bulimia nervosa, Gilles de Ia Tourette Syndrome, vasomotor flushing, cocaine and alcohol addiction, sexual dysfunction, borderline personality disorder, fibromyalgia syndrome, diabetic neuropathic pain, chronic fatigue syndrome, pain, visceral pain, Shy Drager syndrome, Raynaud's syndrome, Parkinson's Disease, and epilepsy.
(FR) L'invention concerne des inhibiteurs doubles hautement sélectifs de recaptage de la sérotonine et de la noradrénaline. Ces composés présentent moins d'effets secondaires et sont utiles dans des compositions et produits servant à traiter divers états pathologiques, notamment la dépression, la fibromyalgie, l'anxiété, le trouble panique, l'agoraphobie, le syndrome de stress post-traumatique, le trouble dysphorique prémenstruel, le trouble déficitaire de l'attention, les troubles obsessionnels compulsifs, le trouble d'anxiété sociale, le trouble d'anxiété généralisée, l'autisme, la schizophrénie, l'obésité, l'anorexie nerveuse, la boulimie nerveuse, le syndrome de Gilles de la Tourette, les bouffées vasomotrices, la cocaïnomanie et l'alcoolisme, la dysfonction sexuelle, le trouble de la personnalité limite, le syndrome de fibromyalgie, la neuropathie diabétique, le syndrome de fatigue chronique, la douleur, la douleur viscérale, le syndrome de Shy-Drager, la maladie de Raynaud, la maladie de Parkinson et l'épilepsie.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
NO20080006NZ564767MXMX/a/2008/000680KR1020080034921IL188614AR057662
VN17874PE2007-0247EP1904434CR48/9661ZA2008/00408JP2009501229
CN101223129CA2615362AU2006270380ID048.2244MYPI 20063344TH89009
IN258/DELNP/2008