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1. (WO2007011411) N-FRAGMENT OF EDEMA FACTOR AS AN ANTIGEN FOR IMMUNIZATION AGAINST ANTHRAX
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2007/011411 International Application No.: PCT/US2005/039799
Publication Date: 25.01.2007 International Filing Date: 04.11.2005
IPC:
C12N 1/20 (2006.01) ,A61K 39/00 (2006.01) ,A61K 39/02 (2006.01) ,A61K 39/07 (2006.01) ,A61K 38/00 (2006.01) ,C12P 21/02 (2006.01) ,C12P 21/04 (2006.01) ,C07H 21/04 (2006.01) ,C07K 14/00 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
1
Micro-organisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving micro-organisms or compositions thereof; Processes of preparing or isolating a composition containing a micro-organism; Culture media therefor
20
Bacteria; Culture media therefor
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
02
Bacterial antigens
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
02
Bacterial antigens
07
Bacillus
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
P
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
21
Preparation of peptides or proteins
02
having a known sequence of two or more amino acids, e.g. glutathione
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
P
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
21
Preparation of peptides or proteins
02
having a known sequence of two or more amino acids, e.g. glutathione
04
Cyclic or bridged peptides or polypeptides, e.g. bacitracin
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
H
SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
21
Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
04
with deoxyribosyl as saccharide radical
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
Applicants:
UNIVERSITY OF ROCHESTER [US/US]; 601 Elmwood Avenue Box OTT Rochester, NY 14642, US (AllExceptUS)
PICHICHERO, Michael, E. [US/US]; US (UsOnly)
ZENG, Mingtao [CN/US]; US (UsOnly)
Inventors:
PICHICHERO, Michael, E.; US
ZENG, Mingtao; US
Agent:
HUIZENGA, David, E.; Needle & Rosenberg, P.C. Suite 1000 999 Peachtree Street Atlanta, GA 30309-3915, US
Priority Data:
60/625,38205.11.2004US
Title (EN) N-FRAGMENT OF EDEMA FACTOR AS AN ANTIGEN FOR IMMUNIZATION AGAINST ANTHRAX
(FR) FRAGMENT N DU FACTEUR OEDEMATOGENE UTILISE COMME ANTIGENE POUR L'IMMUNISATION CONTRE L'ANTHRAX
Abstract:
(EN) Disclosed are compositions and methods for a non-catalytic fragment of Bacillus anthracis edema factor. In particular, this invention provides a peptide or nucleic acid coding for a peptide comprising a non-catalytic fragment of edema factor. This invention further provides methods for using this fragment as an anthrax antigen to elicit an immune response effective in treating or preventing anthrax infection.
(FR) L'invention concerne des compositions et des procédés permettant d'obtenir un fragment non catalytique du facteur oedématogène de Bacillus anthracis. En particulier, l'invention porte sur un peptide ou un acide nucléique codant pour un peptide comprenant un fragment non catalytique du facteur oedématogène. L'invention se rapporte en outre à des procédés permettant d'utiliser ce fragment comme antigène de l'anthrax afin de déclencher une réponse immunitaire efficace pour traiter ou prévenir l'infection par l'anthrax.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)