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1. (WO2007011074) RNA EXPRESSION VECTOR SELECTIVE TO NERVOUS SYSTEM CELL
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2007/011074 International Application No.: PCT/JP2006/315078
Publication Date: 25.01.2007 International Filing Date: 24.07.2006
IPC:
C12N 15/09 (2006.01) ,A01K 67/027 (2006.01) ,C12N 5/10 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
A HUMAN NECESSITIES
01
AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
K
ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
67
Rearing or breeding animals, not otherwise provided for; New breeds of animals
027
New breeds of vertebrates
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5
Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
10
Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells
Applicants:
学校法人日本大学 NIHON UNIVERSITY [JP/JP]; 〒1028275 東京都千代田区九段南四丁目8番24号 Tokyo 8-24, Kudan-minami 4-chome, Chiyoda-ku, Tokyo 1028275, JP (AllExceptUS)
小林 俊亮 KOBAYASHI, Shunsuke [JP/JP]; JP (UsOnly)
安西 偕二郎 ANZAI, Kaijiro [JP/JP]; JP (UsOnly)
Inventors:
小林 俊亮 KOBAYASHI, Shunsuke; JP
安西 偕二郎 ANZAI, Kaijiro; JP
Agent:
小林 浩 KOBAYASHI, Hiroshi; 〒1040028 東京都中央区八重洲二丁目8番7号 福岡ビル9階 阿部・井窪・片山法律事務所 Tokyo c/o ABE, IKUBO & KATAYAMA, Fukuoka Bldg. 9th Fl., 8-7, Yaesu 2-chome, Chuo-ku, Tokyo 1040028, JP
Priority Data:
60/702,01922.07.2005US
Title (EN) RNA EXPRESSION VECTOR SELECTIVE TO NERVOUS SYSTEM CELL
(FR) VECTEUR D’EXPRESSION D’ARN SÉLECTIF POUR UNE CELLULE DU SYSTÈME NERVEUX
(JA) 神経系細胞に選択的なRNA発現ベクター
Abstract:
(EN) Disclosed are a promoter for the expression of RNA in such a manner that is selective to a nervous system cell; a vector bearing the promoter; and a method for the expression of RNA using the vector. RNA such as shRNA can be expressed in such a manner that is selective to a nervous system cell by using the vector.
(FR) La présente invention concerne un promoteur pour l’expression d’ARN d’une manière sélective pour une cellule du système nerveux, un vecteur portant ledit promoteur, et un procédé d’expression d’ARN utilisant ledit vecteur. L’ARN, tel que shARN, peut être exprimé d’une manière qui est sélective pour une cellule du système nerveux utilisant le vecteur.
(JA) 本発明は、神経系細胞選択的にRNAを発現させるプロモーター、前記プロモータを含有するベクターおよび前記ベクターを用いたRNAの発現方法に関する。本発明のベクターを用いることにより、神経系細胞選択的にshRNAなどのRNAを発現させることができる。
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)