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1. (WO2007011072) PREMATURE OVULATION PREVENTIVE AGENT
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2007/011072 International Application No.: PCT/JP2006/314943
Publication Date: 25.01.2007 International Filing Date: 21.07.2006
IPC:
A61K 45/00 (2006.01) ,A61K 31/519 (2006.01) ,A61P 15/06 (2006.01) ,A61P 15/08 (2006.01) ,A61P 43/00 (2006.01) ,C07D 495/04 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
45
Medicinal preparations containing active ingredients not provided for in groups A61K31/-A61K41/132
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
495
having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
505
Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
519
ortho- or peri-condensed with heterocyclic rings
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
15
Drugs for genital or sexual disorders; Contraceptives
06
Antiabortive agents; Labour repressants
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
15
Drugs for genital or sexual disorders; Contraceptives
08
for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
43
Drugs for specific purposes, not provided for in groups A61P1/-A61P41/108
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
495
Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
02
in which the condensed system contains two hetero rings
04
Ortho-condensed systems
Applicants:
武田薬品工業株式会社 TAKEDA PHARMACEUTICAL COMPANY LIMITED [JP/JP]; 〒5410045 大阪府大阪市中央区道修町四丁目1番1号 Osaka 1-1, Doshomachi 4-chome, Chuo-ku, Osaka-shi, Osaka 5410045, JP (AllExceptUS)
古矢 修一 FURUYA, Shuichi [JP/JP]; JP (UsOnly)
日下 雅美 KUSAKA, Masami [JP/JP]; JP (UsOnly)
Inventors:
古矢 修一 FURUYA, Shuichi; JP
日下 雅美 KUSAKA, Masami; JP
Agent:
高島 一 TAKASHIMA, Hajime; 〒5410044 大阪府大阪市中央区伏見町四丁目1番1号 明治安田生命大阪御堂筋ビル Osaka Meiji Yasuda Seimei Osaka Midosuji Bldg. 1-1, Fushimimachi 4-chome Chuo-ku, Osaka-shi Osaka 541-0044, JP
Priority Data:
2005-21297322.07.2005JP
Title (EN) PREMATURE OVULATION PREVENTIVE AGENT
(FR) AGENT PRÉVENTIF DE L’OVULATION PRÉMATURÉE
(JA) 早発排卵の防止剤
Abstract:
(EN) A preventive agent of premature ovulation which may occur during in vitro fertilization or embryo transplantation, the agent comprising a non-peptide compound having an antagonistic effect on a gonadotropin-releasing hormone. The preventive agent shows a low toxicity, can be administered through an oral route, and has an excellent preventive effect on the premature ovulation during in vitro fertilization or embryo transplantation.
(FR) L’invention concerne un agent préventif de l'ovulation prématurée qui peut survenir lors de la fécondation in vitro ou de la transplantation d'embryon. L'agent comprend un composé non peptidique ayant un effet antagoniste sur une hormone libérant la gonadotrophine. L'agent préventif présente une faible toxicité, peut être administré par voie orale et a un excellent effet préventif sur l'ovulation prématurée pendant la fécondation in vitro ou la transplantation d'embryon.
(JA) 本発明は、性腺刺激ホルモン放出ホルモン拮抗作用を有する非ペプチド性化合物を含有してなる体外受精または胚移植施行時における早発排卵の防止剤を提供する。本発明の、体外受精または胚移植施行時における早発排卵の防止剤は、毒性が低く、経口投与でき、優れた体外受精または胚移植施行時における早発排卵の防止効果を有する。
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)
Also published as:
NO20080869MXMX/a/2008/000820KR1020080041662IL188764EP1917978ZA2008/01150
JPWO2007011072US20090048273RU0002419435BRPI0613643CN101272806CA2615795
ES2494842NZ566038AU2006270749ID048.1589IN546/KOLNP/2008